Nair Suraj, Kumar V Suresh, Krishnan Ramesh, Rajan Pooja
Department of Pedodontics and Preventive Dentistry, Vinayaka Missions Sankarachariyar Dental College, Salem, Tamil Nadu, India.
J Pharm Bioallied Sci. 2017 Nov;9(Suppl 1):S82-S84. doi: 10.4103/jpbs.JPBS_75_17.
Bifidobacteria levels in saliva were found to be significantly correlated in adults with dental caries but less information available in the literature regarding its role in children.
The aim is to compare the salivary levels of Bifidobacteria in children who are caries free with that of early childhood caries (ECC) and severe ECC (S-ECC).
Saliva was collected using the tongue-loop method from a total of 60 children between the age group of 3-5 years and they were further divided into 3 groups. In addition, the age and gender of the children, sugar amount in diet, sugar frequency in diet, were recorded.
Bifidobacteria was isolated from all the three groups, but more were from S-ECC, followed by ECC and very few cases of caries-free children and was found to statistically significant ( < 0.001). Salivary levels of Bifidobacteria were significantly correlated with amount of sugar in the diet and frequency of sugar consumption.
Salivary levels of Bifidobacteria were significantly associated with S-ECC and ECC, followed by caries free group. In future, it can be used as a salivary marker for caries risk assesment.
研究发现，成年人唾液中的双歧杆菌水平与龋齿显著相关，但关于其在儿童中的作用，文献报道较少。
比较无龋儿童与患有早期儿童龋（ECC）和重度早期儿童龋（S-ECC）儿童的唾液双歧杆菌水平。
采用舌套法收集了60名3至5岁儿童的唾液，并将他们进一步分为3组。此外，记录了儿童的年龄、性别、饮食中的糖含量和饮食中的糖摄入频率。
所有三组均分离出双歧杆菌，但S-ECC组分离出的更多，其次是ECC组，无龋儿童组分离出的极少，差异具有统计学意义（<0.001）。唾液双歧杆菌水平与饮食中的糖含量和糖摄入频率显著相关。
唾液双歧杆菌水平与S-ECC和ECC显著相关，其次是无龋组。未来，它可作为龋齿风险评估的唾液标志物。
