Inquimbert Camille, Bourgeois Denis, Bravo Manuel, Viennot Stéphane, Tramini Paul, Llodra Juan Carlos, Molinari Nicolas, Dussart Claude, Giraudeau Nicolas, Carrouel Florence
Laboratory "Systemic Health Care", EA4129, University Lyon 1, University of Lyon, 69008 Lyon, France.
Department of Public Health, Faculty of Dental Medicine, University of Montpellier, 34090 Montpellier, France.
Microorganisms. 2019 Sep 5;7(9):319. doi: 10.3390/microorganisms7090319.
Adolescence is closely associated with a high risk of caries. The identification of specific bacteria in an oral microniche, the interdental space of the molars, according to carious risk can facilitate the prediction of future caries and the anticipation of the progression or stabilization of caries in adolescents. A cross-sectional clinical study according to the bacteriological criteria of interdental healthy adolescents and carious risk factors-low and high-using a real-time polymerase chain reaction technique was conducted. The presence of 26 oral pathogens from the interdental microbiota of 50 adolescents aged 15 to 17 years were qualitatively and quantitatively analyzed. Bacteria known to be cariogenic (, spp., , , , , , and ) did not present differences in abundance according to carious risk. Periodontal bacteria from the red complex are positively correlated with carious risk. However, only 3 bacteria-, and -presented a significant increase in the highest group. Estimating the risk of caries associated with bacterial factors in interdental sites of molars in adolescents contributes to the better definition of carious risk status, periodicity and intensity of diagnostic, prevention and restorative services.
青春期与龋齿的高风险密切相关。根据龋齿风险，在口腔微环境（磨牙的牙间隙）中识别特定细菌有助于预测青少年未来的龋齿情况以及预期龋齿的进展或稳定。采用实时聚合酶链反应技术，依据牙间隙健康青少年以及低、高龋齿风险因素的细菌学标准进行了一项横断面临床研究。对50名15至17岁青少年牙间隙微生物群中的26种口腔病原体进行了定性和定量分析。已知的致龋菌（ 、 属、 、 、 、 及 ）在龋齿风险方面的丰度没有差异。红色复合体中的牙周细菌与龋齿风险呈正相关。然而，只有3种细菌—— 、 和 ——在最高风险组中显著增加。评估青少年磨牙牙间隙部位与细菌因素相关的龋齿风险有助于更好地界定龋齿风险状态、诊断、预防和修复服务的周期及强度。
