• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

有症状的先天性巨细胞病毒耳聋:六周抗病毒治疗疗程对听力改善的影响。

Symptomatic congenital Cytomegalovirus deafness: the impact of a six-week course of antiviral treatment on hearing improvement.

作者信息

Mazzaferri Fulvia, Cordioli Maddalena, Conti Michela, Storato Silvia, Be Giorgia, Biban Paolo, Concia Ercole, Merighi Mara

机构信息

Diagnostic and Public Health Department, Infectious Diseases and Tropical Medicine Section, University of Verona, Verona, Italy.

Neonatal Intensive Care Unit, Verona University Hospital, Verona, Italy.

出版信息

Infez Med. 2017 Dec 1;25(4):347-350.

PMID:29286014
Abstract

Congenital Cytomegalovirus infection is the leading non-genetic cause of neurosensory deafness. We compared the outcomes of a treated group of children to an untreated group. The effect of antiviral therapy on hearing improvement between baseline and 2-year follow-up was statistically significant. These results suggest that the benefit of 6-week therapy is not limited to preventing further hearing deterioration.

摘要

先天性巨细胞病毒感染是神经感觉性耳聋的主要非遗传病因。我们将一组接受治疗的儿童的结果与未接受治疗的组进行了比较。抗病毒治疗在基线和2年随访之间对听力改善的效果具有统计学意义。这些结果表明,6周治疗的益处不仅限于预防听力进一步恶化。

相似文献

1
Symptomatic congenital Cytomegalovirus deafness: the impact of a six-week course of antiviral treatment on hearing improvement.有症状的先天性巨细胞病毒耳聋:六周抗病毒治疗疗程对听力改善的影响。
Infez Med. 2017 Dec 1;25(4):347-350.
2
Effect on hearing of oral valganciclovir for asymptomatic congenital cytomegalovirus infection.口服缬更昔洛韦对无症状先天性巨细胞病毒感染的听力影响。
J Trop Pediatr. 2011 Apr;57(2):132-4. doi: 10.1093/tropej/fmq050. Epub 2010 Jun 24.
3
Treatment of symptomatic congenital cytomegalovirus infection with intravenous ganciclovir followed by long-term oral valganciclovir.静脉注射更昔洛韦治疗有症状的先天性巨细胞病毒感染,继以长期口服缬更昔洛韦。
Eur J Pediatr. 2010 Sep;169(9):1061-7. doi: 10.1007/s00431-010-1176-9. Epub 2010 Mar 16.
4
Hearing outcome of infants with congenital cytomegalovirus and hearing impairment.先天性巨细胞病毒感染伴听力障碍婴儿的听力结果。
Arch Dis Child. 2016 May;101(5):433-8. doi: 10.1136/archdischild-2015-309154. Epub 2016 Jan 29.
5
Effect on hearing of ganciclovir therapy for asymptomatic congenital cytomegalovirus infection: four to 10 year follow up.更昔洛韦治疗无症状先天性巨细胞病毒感染对听力的影响:4至10年随访
J Laryngol Otol. 2009 Apr;123(4):391-6. doi: 10.1017/S0022215108003162. Epub 2008 Jun 30.
6
Oral Valganciclovir treatment in a CMV congenital infected infant with sensorineural hearing loss (SNHL) first detected at 4 months of age.口服缬更昔洛韦治疗一名先天性巨细胞病毒感染婴儿,该婴儿在4个月大时首次被检测出患有感音神经性听力损失(SNHL)。
Klin Padiatr. 2009 Dec;221(7):448-9. doi: 10.1055/s-0029-1234076.
7
Oral Valganciclovir Initiated Beyond 1 Month of Age as Treatment of Sensorineural Hearing Loss Caused by Congenital Cytomegalovirus Infection: A Randomized Clinical Trial.口服缬更昔洛韦治疗先天性巨细胞病毒感染引起的感音神经性听力损失:一项随机临床试验。
J Pediatr. 2024 May;268:113934. doi: 10.1016/j.jpeds.2024.113934. Epub 2024 Feb 2.
8
Congenital Cytomegalovirus and Neonatal Herpes Simplex Virus Infections: To Treat or Not to Treat?先天性巨细胞病毒和新生儿单纯疱疹病毒感染:治疗还是不治疗?
Pediatr Infect Dis J. 2019 Jun;38(6S Suppl 1):S60-S63. doi: 10.1097/INF.0000000000002325.
9
A neonate with reduced cytomegalovirus DNA copy number and marked improvement of hearing in the treatment of congenital cytomegalovirus infection.一名先天性巨细胞病毒感染患儿在治疗后巨细胞病毒DNA拷贝数降低且听力显著改善。
J Nippon Med Sch. 2012;79(6):471-7. doi: 10.1272/jnms.79.471.
10
Valganciclovir in Infants with Hearing Loss and Clinically Inapparent Congenital Cytomegalovirus Infection: A Nonrandomized Controlled Trial.缬更昔洛韦治疗伴有听力损失和临床无症状先天性巨细胞病毒感染的婴儿:一项非随机对照试验。
J Pediatr. 2024 May;268:113945. doi: 10.1016/j.jpeds.2024.113945. Epub 2024 Feb 8.

引用本文的文献

1
Ophthalmic Complications, Diagnosis, and Treatment of Congenital Human Cytomegalovirus Infection.先天性人类巨细胞病毒感染的眼科并发症、诊断与治疗
J Clin Med. 2024 Jun 8;13(12):3379. doi: 10.3390/jcm13123379.
2
Role of Valganciclovir in Children with Congenital CMV Infection: A Review of the Literature.缬更昔洛韦在先天性巨细胞病毒感染儿童中的作用:文献综述
Children (Basel). 2023 Jul 19;10(7):1246. doi: 10.3390/children10071246.
3
Treatment of congenital cytomegalovirus infection.先天性巨细胞病毒感染的治疗
Clin Exp Pediatr. 2023 Sep;66(9):384-394. doi: 10.3345/cep.2022.01032. Epub 2022 Dec 28.
4
A Review of Sensorineural Hearing Loss in Congenital Cytomegalovirus Infection.先天性巨细胞病毒感染中感音神经性听力损失的综述
Cureus. 2022 Oct 26;14(10):e30703. doi: 10.7759/cureus.30703. eCollection 2022 Oct.
5
Estimated Cost-effectiveness of Newborn Screening for Congenital Cytomegalovirus Infection in China Using a Markov Model.运用马尔可夫模型评估中国先天性巨细胞病毒感染新生儿筛查的成本效益
JAMA Netw Open. 2020 Dec 1;3(12):e2023949. doi: 10.1001/jamanetworkopen.2020.23949.