Jang Hyungjun, Refatul Haq Muhammad, Kim Youngkyu, Kim Jun, Oh Pyoung-Hwa, Ju Jonghyun, Kim Seok-Min, Lim Jiseok
School of Mechanical Engineering, College of Engineering, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Korea.
School of Mechanical Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan, Gyeongbuk 38541, Korea.
Sensors (Basel). 2017 Dec 29;18(1):83. doi: 10.3390/s18010083.
This study reports a cost-effective method of replicating glass microfluidic chips using a vitreous carbon (VC) stamp. A glass replica with the required microfluidic microstructures was synthesized without etching. The replication method uses a VC stamp fabricated by combining thermal replication using a furan-based, thermally-curable polymer with carbonization. To test the feasibility of this method, a flow focusing droplet generator with flow-focusing and channel widths of 50 µm and 100 µm, respectively, was successfully fabricated in a soda-lime glass substrate. Deviation between the geometries of the initial shape and the vitreous carbon mold occurred because of shrinkage during the carbonization process, however this effect could be predicted and compensated for. Finally, the monodispersity of the droplets generated by the fabricated microfluidic device was evaluated.
本研究报告了一种使用玻璃碳（VC）印章复制玻璃微流控芯片的经济高效方法。无需蚀刻即可合成具有所需微流控微结构的玻璃复制品。该复制方法使用的VC印章是通过将基于呋喃的热固化聚合物的热复制与碳化相结合而制造的。为了测试该方法的可行性，在钠钙玻璃基板上成功制造了一个流动聚焦液滴发生器，其流动聚焦和通道宽度分别为50 µm和100 µm。由于碳化过程中的收缩，初始形状与玻璃碳模具的几何形状之间出现了偏差，然而这种影响是可以预测和补偿的。最后，评估了所制造的微流控装置产生的液滴的单分散性。
