乙状结肠直肠对肠易激综合征中假饲的动力反应。头期证据。

Rectosigmoid motility response to sham feeding in irritable bowel syndrome. Evidence of a cephalic phase.

作者信息

Jepsen J M, Skoubo-Kristensen E, Elsborg L

机构信息

Surgical Dept. I, University Hospital, Arhus Amtssygehus, Denmark.

出版信息

Scand J Gastroenterol. 1989 Jan;24(1):53-6. doi: 10.3109/00365528909092239.

DOI:10.3109/00365528909092239

PMID:2928723

Abstract

Rectosigmoid pressure recordings by means of open-ended perfused catheters were performed on 21 patients with the irritable bowel syndrome (IBS). Motility indexes were calculated in resting conditions, after sham feeding, after a meal, and after 0.5 mg neostigmine intravenously. Each step of stimulation caused a significantly increased motility index compared with the previous step (p less than 0.01). The increase in rectosigmoid pressure activity after sham feeding indicates the existence of a cephalic phase in the postprandial motor response of the colon in IBS.

摘要

使用开放式灌注导管对21例肠易激综合征（IBS）患者进行直肠乙状结肠压力记录。在静息状态、假饲后、进食后以及静脉注射0.5毫克新斯的明后计算运动指数。与前一步相比，每一步刺激均导致运动指数显著增加（p<0.01）。假饲后直肠乙状结肠压力活动的增加表明IBS患者结肠餐后运动反应中存在头期。