Enck P, Whitehead W E, Schuster M M, Wienbeck M
Medizinische Klinik, Universität Düsseldorf.
Dtsch Med Wochenschr. 1988 Mar 25;113(12):459-62. doi: 10.1055/s-2008-1067662.
The clinical symptoms of patients with the irritable bowel syndrome (ICS) frequently do not differ according to present findings from those of patients with lactose malabsorption. To test this observation further in a gastroenterological out-patient clinic, the authors compared the clinical symptoms, psychological features and motor activity in the rectosigmoid in 20 patients with ICS and 21 with lactose malabsorption. It was found that the intestinal symptoms, intestinal motor activity and psychopathology of patients with ICS was nonspecific and occurred equally frequently as those in the malabsorption patients. This casts doubt on the view that psychological factors play a role in the pathogenesis of ICS.
肠易激综合征（ICS）患者的临床症状，根据目前的检查结果，常常与乳糖吸收不良患者的症状并无差异。为了在胃肠病门诊进一步验证这一观察结果，作者比较了20例肠易激综合征患者和21例乳糖吸收不良患者的临床症状、心理特征以及直肠乙状结肠的运动活性。结果发现，肠易激综合征患者的肠道症状、肠道运动活性和精神病理学表现并无特异性，且与吸收不良患者出现的频率相同。这使人怀疑心理因素在肠易激综合征发病机制中起作用这一观点。
