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[洛桑和日内瓦学龄儿童氟化物的尿排泄与食盐氟化的关系]

[Urinary excretion of fluorides in schoolchildren of Lausanne and Geneva in relation to salt fluoridation].

作者信息

Menghini G, de Crousaz P, Steiner M, Helfenstein U, Sener B

出版信息

Schweiz Monatsschr Zahnmed. 1989;99(3):292-8.

PMID:2928744
Abstract

Urinary excretion of fluoride and sodium and urinary flow were studied in 230 schoolchildren (average age: 11.1 years) in the following situation: in 1984 and 1988 in Geneva, 1 year and 5 years after the introduction of fluoridated domestic salt (250 mg/kg), and in 1985 in Lausanne, 15 years after the general introduction of salt fluoridation for this city and its surrounding canton (Vaud). Among consumers of fluoridated salt, the average excretion of F ion during morning and afternoon was 15.4 and 43.7 micrograms F/h, respectively, in Geneva (1988) and 26.4 and 49.9 micrograms F/h, respectively, in Lausanne (1985). Among non-consumers of fluoridated domestic salt, excretion values during morning and afternoon were 9.9 and 20.7 micrograms F/h, respectively, in Geneva (1988), and 18.4 and 26.1 micrograms F/h, respectively, in Lausanne. Between 1984 and 1988, an increase in fluoride excretion was observed in schoolchildren of Geneva. During approximately 10 night hours, 8.8 to 16.4 micrograms F/h were excreted in Geneva, but F-salt consumers in Lausanne excreted 25.8 micrograms F/h. Averages of sodium excretion varied between 80 and 144 mg Na/h at daytime and between and 81 mg Na/h at night.

摘要

对230名学童(平均年龄:11.1岁)在以下情况下的氟化物、钠的尿排泄量及尿流量进行了研究:1984年和1988年在日内瓦,分别是引入含氟家用盐(250毫克/千克)1年后和5年后;1985年在洛桑,是该市及其周边州(沃州)普遍引入食盐氟化15年后。在食用含氟盐的人群中,1988年在日内瓦,上午和下午氟离子的平均排泄量分别为15.4微克氟/小时和43.7微克氟/小时,1985年在洛桑分别为26.4微克氟/小时和49.9微克氟/小时。在未食用含氟家用盐的人群中,1988年在日内瓦,上午和下午的排泄量分别为9.9微克氟/小时和20.7微克氟/小时,在洛桑分别为18.4微克氟/小时和26.1微克氟/小时。1984年至1988年期间,日内瓦的学童氟排泄量有所增加。在大约10个夜间小时里,日内瓦的氟排泄量为8.8至16.4微克氟/小时,但洛桑食用含氟盐的人群排泄量为25.8微克氟/小时。白天钠排泄量的平均值在80至144毫克钠/小时之间,夜间在81毫克钠/小时之间。

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