Marthaler T M, Steiner M, Menghini G, De Crousaz P
Department of Preventive Dentistry, Periodontology and Cariology, University of Zurich, Switzerland.
Caries Res. 1995;29(1):26-34. doi: 10.1159/000262036.
The purpose of this study was to compare urinary fluoride excretion with fluoride ingestion in children who had either a low fluoride intake or received supplemental fluoride through salt or water. The urinary samples were collected in two ways. In procedure A, urine was collected in the morning, at noon and during the afternoon. This covered a continuous period of approximately 7 h from the beginning to the end of the school day. In procedure B, morning, afternoon and night samples were collected. The morning and afternoon samples were obtained under supervision at school. Procedure B was more useful than procedure A for monitoring salt fluoridation projects. Children with a history of low fluoride intake excreted a mean of 10 micrograms F/h during the night and the morning, but 13-16 micrograms F/h after the main meal. Children in a water-fluoridated town or in comprehensive salt fluoridation programs excreted between 19 and 33 micrograms F/h. However, after the intake of meals prepared with fluoridated salt (250 ppm F) the mean excretion of fluoride ranged between 31 and 49 micrograms F/h. The levels of excretion corresponded with the levels of fluoride intake and meal patterns in the various groups.
本研究的目的是比较氟摄入量低或通过食盐或水补充氟的儿童的尿氟排泄量与氟摄入量。尿样通过两种方式收集。在方法A中，于早晨、中午和下午收集尿液。这涵盖了从上学日开始到结束约7小时的连续时间段。在方法B中，收集早晨、下午和夜间的样本。早晨和下午的样本在学校监督下采集。方法B对于监测食盐加氟项目比方法A更有用。氟摄入量低的儿童在夜间和早晨平均每小时排泄10微克氟，但在正餐之后为每小时13 - 16微克氟。在水加氟城镇或综合食盐加氟项目中的儿童每小时排泄19至33微克氟。然而，摄入用含氟食盐（250 ppm氟）烹制的膳食后，氟的平均排泄量在每小时31至49微克之间。排泄水平与各群体的氟摄入量和饮食模式相符。
