未包被的recA-DNA复合物的扫描隧道显微镜观察
Scanning tunneling microscopy of uncoated recA-DNA complexes.
作者信息
Amrein M, Dürr R, Stasiak A, Gross H, Travaglini G
机构信息
Institute of Cell Biology, Swiss Federal Institute of Technology, Zurich, Switzerland.
出版信息
Science. 1989 Mar 31;243(4899):1708-11. doi: 10.1126/science.2928803.
PMID:2928803
Abstract
Uncoated recA-DNA complexes were imaged with the scanning tunneling microscope (STM). The images, which reveal the right-handed helical structure of the complexes with subunits clearly resolved, are comparable in quality to STM images of metal-coated specimens. Possible conduction mechanisms that allow STM imaging of biological macromolecules are discussed.
摘要
使用扫描隧道显微镜（STM）对未包被的recA-DNA复合物进行成像。这些图像清晰地显示了复合物的右手螺旋结构，其亚基清晰可辨，图像质量与金属包被标本的STM图像相当。文中讨论了使STM能够对生物大分子进行成像的可能传导机制。
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