Böse Brit, Rohde Veit, Fiss Ingo, Freimann Florian Baptist
Department of Neurosurgery, University Hospital of Göttingen, 37075, Göttingen, Germany.
Acta Neurochir (Wien). 2018 Mar;160(3):519-524. doi: 10.1007/s00701-017-3439-y. Epub 2017 Dec 29.
Intraperitoneal pressure (IPP) counteracts the diversion of cerebrospinal fluid (CSF) from the cranial to the peritoneal compartment during ventriculoperitoneal shunting. Animal studies suggest that the intrinsic IPP exceeds the intraperitoneal hydrostatic pressure. The intrinsic IPP in mobile patients is relevant for shunt therapy, but data about it is not available.
The IPP was measured indirectly in 25 mobile subjects (13 female) by applying a standard intravesical pressure measurement technique. Measurements were carried out in reference to the navel (supine position) and the xiphoid (upright position). Results were adjusted for the intraperitoneal hydrostatic pressure and correlated afterward with general body measures.
The corrected mean (SD) IPP measured in the supine position was 4.4 (4.5) cm HO, and the mean (SD) upright IPP was 1.6 (7.8) cm HO (p = 0.02). A positive correlation was found between the body mass index (BMI) and the IPP in the upright (r = 0.51) and supine (r = 0.65) body positions, and between the abdominal circumference and the IPP in the supine position (r = 0.63).
The intrinsic IPP in mobile subjects exceeds the intraperitoneal hydrostatic pressure. Thus, the intrinsic IPP counteracts the diversion of CSF into the peritoneal compartment. The intrinsic IPP is correlated with mobile patients' general body measures.
在脑室 - 腹腔分流术中，腹腔内压力（IPP）可抵消脑脊液（CSF）从颅腔向腹腔腔隙的分流。动物研究表明，固有IPP超过腹腔静水压力。活动患者的固有IPP与分流治疗相关，但尚无相关数据。
采用标准膀胱内压力测量技术对25名活动受试者（13名女性）间接测量IPP。测量是参照肚脐（仰卧位）和剑突（直立位）进行的。结果针对腹腔静水压力进行了校正，随后与全身测量指标进行相关性分析。
仰卧位测量的校正后平均（标准差）IPP为4.4（4.5）cmH₂O，直立位平均（标准差）IPP为1.6（7.8）cmH₂O（p = 0.02）。在直立位（r = 0.51）和仰卧位（r = 0.65）时，体重指数（BMI）与IPP之间以及仰卧位时腹围与IPP之间均发现正相关。
活动受试者的固有IPP超过腹腔静水压力。因此，固有IPP可抵消脑脊液向腹腔腔隙的分流。固有IPP与活动患者的全身测量指标相关。
