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Single-Molecule Fluorescence Reveals the Oligomerization and Folding Steps Driving the Prion-like Behavior of ASC.单分子荧光揭示了驱动 ASC 朊病毒样行为的寡聚化和折叠步骤。
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Ultrafast Protein Folding in Membrane-Mimetic Environments.在类脂双层环境中的超快蛋白质折叠。
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Soft Interactions with Model Crowders and Non-canonical Interactions with Cellular Proteins Stabilize RNA Folding.与模型分子的软相互作用和与细胞蛋白的非规范相互作用稳定 RNA 折叠。
J Mol Biol. 2018 Feb 16;430(4):509-523. doi: 10.1016/j.jmb.2017.10.030. Epub 2017 Nov 8.
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Stress-induced Pseudouridylation Alters the Structural Equilibrium of Yeast U2 snRNA Stem II.应激诱导的假尿嘧啶核苷修饰改变了酵母 U2 snRNA 茎 II 的结构平衡。
J Mol Biol. 2018 Feb 16;430(4):524-536. doi: 10.1016/j.jmb.2017.10.021. Epub 2017 Oct 24.
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Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly.两种致病的 SNAP-25B 突变选择性地损害 SNARE 羧基末端组装。
J Mol Biol. 2018 Feb 16;430(4):479-490. doi: 10.1016/j.jmb.2017.10.012. Epub 2017 Oct 19.
6
Thermodynamics and Kinetics of Single-Chain Monellin Folding with Structural Insights into Specific Collapse in the Denatured State Ensemble.单链莫奈林折叠的热力学和动力学:变性状态总体中特定折叠的结构见解。
J Mol Biol. 2018 Feb 16;430(4):465-478. doi: 10.1016/j.jmb.2017.09.009. Epub 2017 Sep 18.
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Protein Folding Mediated by Trigger Factor and Hsp70: New Insights from Single-Molecule Approaches.由触发因子和 Hsp70 介导的蛋白质折叠:单分子方法的新见解。
J Mol Biol. 2018 Feb 16;430(4):438-449. doi: 10.1016/j.jmb.2017.09.004. Epub 2017 Sep 11.
8
Exploring the Denatured State Ensemble by Single-Molecule Chemo-Mechanical Unfolding: The Effect of Force, Temperature, and Urea.通过单分子化学机械解折叠探索变性状态集合体:力、温度和脲的影响。
J Mol Biol. 2018 Feb 16;430(4):450-464. doi: 10.1016/j.jmb.2017.07.022. Epub 2017 Aug 4.
9
A Survey of DDX21 Activity During Rev/RRE Complex Formation.DDX21 在 Rev/RRE 复合物形成过程中的活性研究综述
J Mol Biol. 2018 Feb 16;430(4):537-553. doi: 10.1016/j.jmb.2017.06.023. Epub 2017 Jul 10.
10
Transition Path Times Measured by Single-Molecule Spectroscopy.通过单分子光谱学测量的转变路径时间。
J Mol Biol. 2018 Feb 16;430(4):409-423. doi: 10.1016/j.jmb.2017.05.018. Epub 2017 May 25.

Editorial Overview: Single-Molecule Approaches up to Difficult Challenges in Folding and Dynamics.

作者信息

Zhang Yongli, Ha Taekjip, Marqusee Susan

机构信息

Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520, United States.

Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD 21205, United States; Department of Biophysics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD 21205, United States; Department of Biomedical Engineering, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD 21205, United States.

出版信息

J Mol Biol. 2018 Feb 16;430(4):405-408. doi: 10.1016/j.jmb.2017.12.019. Epub 2017 Dec 27.

DOI:10.1016/j.jmb.2017.12.019
PMID:29288633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5858691/
Abstract
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