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采用 UPLC-Q-TOF-MS 对黄花野牡丹进行化学成分分析及其体外抗氧化活性研究。

Chemical profiling of Malva verticillata L. by UPLC-Q-TOF-MS and their antioxidant activity in vitro.

机构信息

College of Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, China.

College of Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, China; Inner Mongolia Research Institute of Traditional Mongolian Medicine Engineering Technology, Tongliao, 028000, China.

出版信息

J Pharm Biomed Anal. 2018 Feb 20;150:420-426. doi: 10.1016/j.jpba.2017.12.044. Epub 2017 Dec 24.

DOI:10.1016/j.jpba.2017.12.044
PMID:29289893
Abstract

Malva verticillata L. (M. verticillata) is an edible medicinal plant. Its dry, mature seeds are used in Traditional Mongolian Medicine. Nevertheless, detailed information regarding its chemical composition remains scarce. In this study, nineteen compounds were identified preliminarily using a UPLC-Q-TOF-MS method. All of the compounds from M. verticillata are reported for the first time. M. verticillata is shown to be a rich source of phenolics, and the total phenolic content in the leaves, stems and seeds is 110.32 ± 3.45 mg GAE/g extract, 97.98 ± 4.19 mg GAE/g extract and 40.85 ± 7.63 mg GAE/g extract, respectively. The leaves are ideal for scavenging ABTS free radicals and possess ferric reducing antioxidant power, and the seeds are ideal for scavenging DPPH free radicals. M. verticillata is a rich source of natural antioxidants. These findings support the notion that M. verticillata is a functional food and can be used in nutraceutical applications.

摘要

马蔺(Malva verticillata L.)是一种可食用的药用植物。其干燥成熟的种子被用于传统蒙药。然而,关于其化学成分的详细信息仍然很少。在这项研究中,使用 UPLC-Q-TOF-MS 方法初步鉴定了 19 种化合物。马蔺中的所有化合物均为首次报道。马蔺富含酚类化合物,其叶子、茎和种子中的总酚含量分别为 110.32±3.45、97.98±4.19 和 40.85±7.63 mg GAE/g 提取物。叶子是清除 ABTS 自由基和具有铁还原抗氧化能力的理想选择,而种子是清除 DPPH 自由基的理想选择。马蔺是天然抗氧化剂的丰富来源。这些发现支持了马蔺是一种功能性食品并可用于营养保健品应用的观点。

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