Okahata H, Nishi Y, Muraki K, Arai M, Kubo N, Sumii K, Miyachi Y, Ueda K
Department of Pediatrics, Ohtake National Hospital, Japan.
Acta Endocrinol (Copenh). 1989 Mar;120(3):374-8. doi: 10.1530/acta.0.1200374.
The effects of individual food constituents on antral gastrin-like immunoreactivity concentrations were studied in young rats. Rats aged 7 to 20 days were given only rat breast milk and then weaned by various nutrients (regular laboratory chow, protein (ovalbumin)-, fat- or carbohydrate (starch)-rich food). Rats receiving rat breast milk only until 27 days of age were also studied. In rats on regular laboratory chow, antral gastrin-like immunoreactivity increased and reached adult levels on day 25. In rats on ovalbumin, fat-rich food or starch, it increased on day 23 but dropped thereafter. The increment by laboratory chow was higher than that by the individual nutrients. No increase was observed during milk feeding alone. Gel filtration of antral gastrin-like immunoreactivity from 25-day-old rats on laboratory chow or three essential nutrients showed the same results.
研究了单一食物成分对幼鼠胃窦胃泌素样免疫反应性浓度的影响。给7至20日龄的大鼠仅喂食鼠母乳，然后用各种营养素（常规实验室饲料、富含蛋白质（卵清蛋白）、脂肪或碳水化合物（淀粉）的食物）使其断奶。还研究了仅在27日龄前喂食鼠母乳的大鼠。食用常规实验室饲料的大鼠，胃窦胃泌素样免疫反应性增加，并在第25天达到成年水平。食用卵清蛋白、富含脂肪的食物或淀粉的大鼠，其胃窦胃泌素样免疫反应性在第23天增加，但此后下降。实验室饲料引起的增加高于单一营养素引起的增加。单独喂食母乳期间未观察到增加。对食用实验室饲料或三种必需营养素的25日龄大鼠的胃窦胃泌素样免疫反应性进行凝胶过滤，结果相同。
