UWA Dental School, University of Western Australia, Nedlands, WA, Australia.
Private Practice, Coffs Harbour, NSW, Australia.
J Oral Pathol Med. 2018 Mar;47(3):281-285. doi: 10.1111/jop.12675. Epub 2018 Jan 18.
Oral dysesthesia (burning mouth syndrome) is characterized by a burning-like sensation of the oral mucosa. The etiology of this disorder is still unknown, however, associations with oral fungal carriage have been proposed and applied clinically. The aim of the this study was to compare oral Candida carriage in patients with oral dysesthesia with Candida carriage in patients with other commonly diagnosed oral diseases to clarify the relationship between Candida and oral dysesthesia.
In total, 441 patients in total including 79 patients diagnosed with oral dysesthesia were included in this study. A retrospective analysis of mycological investigations undertaken in patients with clinically diagnosed oral dysesthesia compared with other oral conditions was undertaken.
Oral carriage of Candida was found in 63.3% (50 of 79) of patients with oral dysesthesia. The frequency of carriage and oral load of Candida were not significantly increased in patients with oral dysesthesia relative to the other conditions assessed. Patients with clinical signs of fungal infection or xerostomia presented with increased carriage of Candida.
There is no association between oral dysesthesia and the presence or load of oral Candida.
口腔感觉异常（灼口综合征）的特征为口腔黏膜有烧灼感。该疾病的病因仍不清楚，但已提出与口腔真菌感染有关，并已应用于临床。本研究的目的是比较口腔感觉异常患者与其他常见诊断的口腔疾病患者的口腔念珠菌携带情况，以阐明念珠菌与口腔感觉异常之间的关系。
共纳入 441 例患者，包括 79 例口腔感觉异常患者。对临床诊断为口腔感觉异常的患者进行的真菌学检查进行回顾性分析，并与其他口腔状况进行比较。
口腔感觉异常患者中，口腔念珠菌携带率为 63.3%（50/79）。与评估的其他疾病相比，口腔感觉异常患者的念珠菌携带率和口腔负荷均无显著增加。有真菌感染或口干临床体征的患者携带念珠菌增加。
口腔感觉异常与口腔念珠菌的存在或负荷无关。
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