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神经白塞病中的多模态诱发电位:两例病例的纵向研究

Multimodal evoked potentials in neuro-Behçet: a longitudinal study of two cases.

作者信息

Rizzo P A, Valle E, Mollica M A, Sanarelli L, Pozzessere G

机构信息

Institute of Clinical Neurology, La Sapienza University, Rome, Italy.

出版信息

Acta Neurol Scand. 1989 Jan;79(1):18-22. doi: 10.1111/j.1600-0404.1989.tb03703.x.

DOI:10.1111/j.1600-0404.1989.tb03703.x
PMID:2929269
Abstract

Two neuro-Behçet patients have been studied, over a period of several months, by means of peroneal and median somatosensory- (SEP), brainstem auditory- (BAEP), and visual- (VEP) evoked potentials. In both patients, peroneal SEP showed evidence of a pathological reduction in the central conduction velocity without a related deep sensation impairment, while VEP changes were consistent with the visual disorders. Conversely, BAEP and median SEP findings did not show disease-related abnormalities. The observed anomalies were detectable irrespective of the clinical phase of the disease. Thus, evoked potential assessment is useful in providing objective evidence for evaluating and monitoring CNS damage in neuro-Behçet's syndrome.

摘要

我们对两名神经白塞病患者进行了为期数月的研究,采用腓总神经和正中神经体感诱发电位(SEP)、脑干听觉诱发电位(BAEP)以及视觉诱发电位(VEP)。在这两名患者中,腓总神经SEP显示中枢传导速度病理性降低,但无相关深部感觉障碍,而VEP变化与视觉障碍一致。相反,BAEP和正中神经SEP结果未显示与疾病相关的异常。无论疾病处于临床哪个阶段,所观察到的异常均能被检测到。因此,诱发电位评估有助于为评估和监测神经白塞病综合征中枢神经系统损伤提供客观证据。

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