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[银屑病的治疗:过去与现在]

[Treatment of psoriasis: before and now].

作者信息

Osmancevic Amra, Ståhle Mona

机构信息

Sahlgrenska Universitetssjukhuset - Hudkliniken Göteborg, Sweden Sahlgrenska Universitetssjukhuset - Hudkliniken Göteborg, Sweden.

Karolinska Universitetssjukhuset - Hudkliniken Stockholm, Sweden Karolinska Universitetssjukhuset - Hudkliniken Stockholm, Sweden.

出版信息

Lakartidningen. 2017 Nov 21;114:EU6Y.

PMID:29292946
Abstract

Treatment of psoriasis: before and now  Psoriasis is a multisystem inflammatory disease primarily affecting the skin. Despite its prevalence and considerable effect on quality of life, psoriasis is still underdiagnosed and undertreated. Many patients seek initial evaluation and treatment at primary care level and therefore it is important to know that treatment of psoriasis has advanced tremendously in recent years. Decisions on psoriasis management should be based on assessment of disease severity and phenotype, the existence of physical and psychological comorbidities, the need for referral to dermatologist for specialist care, the patient's preferences and, when possible, identification and elimination of psoriasis trigger factors. Individual treatment goals should be agreed with the patient and treatment should aim to achieve these goals. An individualized, patient centered approach based on the potential of current treatments and a good interpersonal communication between patient and doctor, is essential for effective management of psoriasis.

摘要

银屑病的治疗

过去与现在 银屑病是一种主要影响皮肤的多系统炎症性疾病。尽管其患病率高且对生活质量有相当大的影响,但银屑病仍存在诊断不足和治疗不足的情况。许多患者在初级保健层面寻求初始评估和治疗,因此了解近年来银屑病的治疗有了巨大进展很重要。银屑病管理决策应基于对疾病严重程度和表型的评估、身心合并症的存在情况、转诊至皮肤科医生接受专科护理的必要性、患者的偏好,以及尽可能识别和消除银屑病触发因素。应与患者商定个体治疗目标,治疗应旨在实现这些目标。基于当前治疗的潜力以及患者与医生之间良好的人际沟通采取个体化、以患者为中心的方法,对于银屑病的有效管理至关重要。

相似文献

1
[Treatment of psoriasis: before and now].[银屑病的治疗:过去与现在]
Lakartidningen. 2017 Nov 21;114:EU6Y.
2
Asian consensus on assessment and management of mild to moderate plaque psoriasis with topical therapy.亚洲共识:轻度至中度斑块型银屑病的外用药物治疗评估与管理。
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Diagnosis and management of psoriasis.银屑病的诊断与管理
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Practical management of psoriasis in the elderly: epidemiology, clinical aspects, quality of life, patient education and treatment options.老年银屑病的实际管理:流行病学、临床方面、生活质量、患者教育及治疗选择
Drugs Aging. 2002;19(11):847-63. doi: 10.2165/00002512-200219110-00003.
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[Therapy options for psoriasis in childhood and adolescence].[儿童及青少年银屑病的治疗选择]
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Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling.姜黄素通过抑制角质形成细胞增殖和 JAK1/STAT3 信号通路炎症基因表达缓解银屑病样炎症。
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