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立体定向放射外科和立体定向体部放射治疗中的质量与安全:还能做得更多吗?

Quality and safety in stereotactic radiosurgery and stereotactic body radiation therapy: can more be done?

作者信息

Solberg Timothy D, Medin Paul M

机构信息

Division of Medical Physics and Engineering, Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas TX, USA.

出版信息

J Radiosurg SBRT. 2011;1(1):13-19.

Abstract

Stereotactic radiosurgery (SRS) has been an effective modality for the treatment of benign and malignant cranial disease for 50 years. Increasingly, the stereotactic approach, ablative doses of radiation delivered in a highly focused manner to a target of interest, is being applied in a number of extracranial disease sites. Stereotactic body radiation therapy (SBRT) holds significant potential for improving tumor control rates across a range of locations and histologies. Both SRS and SBRT require specialized technology, meticulous procedures, and dedicated personnel. Several recent high-profile medical radiation events have generated considerable attention within the media, and serve to remind the profession that close attention to ongoing quality improvement is a fundamental responsibility. The purpose of this manuscript is to provide some recommendations for SRS / SBRT processes and procedures that may be beneficial in understanding and reducing risks inherent to the modalities.

摘要

50年来,立体定向放射外科(SRS)一直是治疗良性和恶性颅脑疾病的有效方法。越来越多地,这种以高度聚焦方式向感兴趣的靶区给予消融剂量辐射的立体定向方法正被应用于多个颅外疾病部位。立体定向体部放射治疗(SBRT)在提高一系列部位和组织学类型肿瘤的控制率方面具有巨大潜力。SRS和SBRT都需要专门的技术、细致的操作程序和专业的人员。最近几起备受瞩目的医疗辐射事件引起了媒体的广泛关注,并提醒该行业密切关注持续的质量改进是一项基本责任。本手稿的目的是为SRS/SBRT的流程和程序提供一些建议,这些建议可能有助于理解和降低这些方法固有的风险。

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