Aslan Hulya, Pourbagher Aysin
Department of Radiology, Faculty of Medicine, Baskent University, Adana Dr. Turgut Noyan Teaching and Medical Research Center, Dadaloglu Mh, Adana, Turkey.
J Clin Imaging Sci. 2017 Nov 30;7:42. doi: 10.4103/jcis.JCIS_65_17. eCollection 2017.
Hematological malignancies very rarely involve the breast. The aim of this study is to retrospectively evaluate B-mode ultrasound (US) and elastography (ES) findings of breast involvement by hematologic malignancies with clinical outcomes.
All core-needle biopsy results that were performed at our tertiary breast center from January 2013 to September 2016 were searched. Our search revealed 9 patients with breast involvement either by leukemia or lymphoma. All patients were examined using B-mode US and ES. US and ES findings were analyzed with the consensus of two radiologists, and clinical outcomes were noted.
The mean age of the study population was 41.6 years (range, 20-83 years). Two patients showed diffuse hypoechoic parenchymal infiltration. The elasticity assessments of these lesions were soft and intermediate. The remaining 7 patients had mass lesions. The elasticity assessment of these masses according to Breast Imaging Reporting and Data System US was as follows: Soft ( = 1), intermediate ( = 4), high ( = 2).
It is important to consider that hematologic malignancies may appear as soft or intermediate lesions on ES. Patients' history and clinical background should help us to consider breast involvement. In addition, the clinical outcomes may not be related with elasticity assessments.
血液系统恶性肿瘤极少累及乳腺。本研究旨在回顾性评估血液系统恶性肿瘤累及乳腺的B超（US）和弹性成像（ES）表现及其临床结局。
检索2013年1月至2016年9月在我们的三级乳腺中心进行的所有粗针活检结果。我们的检索发现9例乳腺受白血病或淋巴瘤累及的患者。所有患者均接受B超和弹性成像检查。由两名放射科医生共同分析超声和弹性成像结果，并记录临床结局。
研究人群的平均年龄为41.6岁（范围20 - 83岁）。2例表现为弥漫性低回声实质浸润。这些病变的弹性评估为软和中等。其余7例有肿块病变。根据乳腺影像报告和数据系统超声对这些肿块的弹性评估如下：软（=1）、中等（=4）、硬（=2）。
重要的是要考虑到血液系统恶性肿瘤在弹性成像上可能表现为软或中等病变。患者的病史和临床背景应有助于我们考虑乳腺受累情况。此外，临床结局可能与弹性评估无关。
