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使用可生物降解的胶原-糖胺聚糖共聚物基质植入物减少斜视手术术后纤维化

Use of biodegradable collagen-glycosaminoglycan copolymer matrix implant to reduce postoperative fibrosis in strabismus surgery.

作者信息

Dos Santos Martins Thiago Gonçalves, de Azevedo Costa Ana Luiza Fontes, Centelhas Antonio Carlos, Dos Santos Martins Diogo Gonçalves

机构信息

Department of Ophthalmology, Federal University of Sao Paulo, São Paulo, Brazil.

Department of Ophthalmology, CRMED, Municipal Hospital Nise da Silveira, Rio de Janeiro, Brazil.

出版信息

Taiwan J Ophthalmol. 2017 Oct-Dec;7(4):227-229. doi: 10.4103/tjo.tjo_75_17.

DOI:10.4103/tjo.tjo_75_17
PMID:29296557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5747235/
Abstract

The occurrence of restrictive strabismus after conjunctival surgeries is widely described in the literature. Fibrosis causes adherence of the conjunctiva to the Tenon's capsule, intermuscular membrane, adipose orbital tissue, sclera, and extraocular muscle tissue. Fibrosis causes adherence of the conjunctiva to the Tenon's capsule, intermuscular membrane, adipose orbital tissue, sclera, and extraocular muscle tissue. We report a case of the use of a biodegradable collagen-glycosaminoglycan copolymer matrix implant (Ologen®) as an alternative adjuvant, used as a spacer to mechanically separate the subconjunctival and episcleral tissues to prevent fibrosis in a patient undergoing a surgical correction for a strabismus with a restrictive component due to previous surgeries of pterygium excision.

摘要

结膜手术后发生限制性斜视在文献中有广泛描述。纤维化导致结膜与眼球筋膜囊、肌间膜、眶脂肪组织、巩膜和眼外肌组织粘连。纤维化导致结膜与眼球筋膜囊、肌间膜、眶脂肪组织、巩膜和眼外肌组织粘连。我们报告了一例使用可生物降解的胶原-糖胺聚糖共聚物基质植入物(Ologen®)作为替代佐剂的病例,该植入物用作间隔物,以机械方式分离结膜下和巩膜上组织,从而防止一名因先前翼状胬肉切除手术而患有伴有限制性成分的斜视的患者发生纤维化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49de/5747235/5db722c581a6/TJO-7-227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49de/5747235/037ae825c3ce/TJO-7-227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49de/5747235/5db722c581a6/TJO-7-227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49de/5747235/037ae825c3ce/TJO-7-227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49de/5747235/5db722c581a6/TJO-7-227-g002.jpg

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Use of biodegradable collagen-glycosaminoglycan copolymer matrix implant to reduce postoperative fibrosis in strabismus surgery.使用可生物降解的胶原-糖胺聚糖共聚物基质植入物减少斜视手术术后纤维化
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本文引用的文献

1
Using a collagen matrix implant (Ologen) versus mitomycin-C as a wound healing modulator in trabeculectomy with the Ex-PRESS mini glaucoma device: a 12-month retrospective review.在 Ex-PRESS 微型青光眼装置小梁切除术中使用胶原基质植入物 (Ologen) 与丝裂霉素 C 作为伤口愈合调节剂:一项 12 个月的回顾性研究。
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Complications of strabismus surgery.
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Scar remodeling after strabismus surgery.斜视手术后的瘢痕重塑。
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Plastic implants in muscle surgery: a study of the possible use of plastic materials in the management of extraocular motility restrictions.肌肉手术中的塑料植入物:关于塑料材料在治疗眼球运动受限方面可能应用的研究。
Trans Am Ophthalmol Soc. 1967;65:393-470.