Steketee R W, Reid S, Cheng T, Stoebig J S, Harrington R G, Davis J P
Division of Field Services, Centers for Disease Control, Atlanta, GA 30333.
Am J Public Health. 1989 Apr;79(4):485-90. doi: 10.2105/ajph.79.4.485.
In the 19-month period September 1983-March 1985, three outbreaks of giardiasis occurred in one large child day care center. Control measures instituted during each outbreak included case finding; pharmacologic treatment and follow-up testing of stool specimens for cases of giardia infection in day care children and staff, and their household contacts; facilitating and stressing personal and environmental hygiene, including altering diapering practices and teaching appropriate hand washing techniques. In the first, second, and third outbreaks, overall attack rates (stool analysis positive for Giardia lamblia) were determined for those persons with greater than or equal to 2 stool specimens submitted; attack rates in children were 47, 17, and 37 per cent, respectively; for tested staff, the rates were 35, 13, and 9 per cent; and for tested household contacts were 18, 9, and 5 per cent. Attack rates were highest for ambulatory diapered children, children attending the day care center greater than or equal to 40 hours per week, and children who were infected with G. lamblia in the most recent previous outbreak. Despite extensive efforts to identify cases, a cure rate of greater than 90 per cent in treated cases, and improvements in personal and environmental hygiene practices, G. lamblia infections recurred in outbreak proportions.
在1983年9月至1985年3月的19个月期间,一家大型儿童日托中心发生了3起贾第虫病疫情。每次疫情期间采取的控制措施包括病例发现;对日托儿童、工作人员及其家庭接触者中的贾第虫感染病例进行药物治疗和粪便标本的后续检测;促进并强调个人和环境卫生,包括改变换尿布习惯和教授适当的洗手技巧。在第一起、第二起和第三起疫情中,对提交了两份及以上粪便标本的人员确定了总体发病率(粪便分析中兰氏贾第鞭毛虫呈阳性);儿童的发病率分别为47%、17%和37%;接受检测的工作人员的发病率分别为35%、13%和9%;接受检测的家庭接触者的发病率分别为18%、9%和5%。动态换尿布儿童、每周在日托中心出勤40小时及以上的儿童以及在上一次疫情中感染过兰氏贾第鞭毛虫的儿童的发病率最高。尽管为识别病例付出了巨大努力,治疗病例的治愈率超过90%,并且个人和环境卫生习惯有所改善,但兰氏贾第鞭毛虫感染仍以疫情规模再次出现。