Mutua Ernest Muthami, Gitonga Moses Mwangi, Mbuthia Beth, Muiruri Nelly, Cheptum Joyce Jebet, Maingi Thomas
School of Health Sciences, Dedan Kimathi University of Technology, Nyeri, Kenya.
Nyeri Provincial General Hospital, Nyeri, Kenya.
Pan Afr Med J. 2014 Aug 5;18:278. doi: 10.11604/pamj.2014.18.278.4308. eCollection 2014.
Uncontrolled hypertension is a leading modifiable risk factor for cardiovascular disease morbidity and mortality. Data on adequacy of blood pressure control in Kenya is scarce. This study aimed at assessing the level of blood pressure control among hypertensive patients on follow-up in a regional referral hospital.
Data regarding blood pressure, antihypertensive medication use, and comorbidities was abstracted from medical records of 452 hypertensive patients seen in Nyeri Provincial General Hospital between January and March 2013. Adequate blood pressure control was defined as a systolic pressure<140 mmHg (<130 mmHg for diabetic hypertensive patients) and a diastolic pressure<90 mmHg (<80 mmHg for diabetic hypertensive patients). Data was entered and analyzed using STATA 9 (StataCorp, Inc, Texas, USA).
Only 33.4% of patients had a blood pressure within the recommended limits. In multivariate analysis, using a calcium channel blocker was significantly associated with good blood pressure control (OR, 2.1; 95% CI, 1.4, 3.3). On the other hand, old age (≥60 years), being diabetic, and the use of three or more antihypertensive drugs were associated with reduced odds of good blood pressure control (OR, 0.64; 95% CI, 0.43; OR, 0.54; 95% CI, 0.36, 0.81; and OR, 0.41; 95% CI, 0.26, 0.64, respectively).
Poorly controlled blood pressure is an important public health concern among hypertensive patients in this region. Elderly patients, those with diabetes, and those on multidrug regimens are at higher risk for poor blood pressure control and warrant closer attention.
未控制的高血压是心血管疾病发病和死亡的主要可改变危险因素。肯尼亚关于血压控制充分性的数据稀缺。本研究旨在评估一家地区转诊医院中接受随访的高血压患者的血压控制水平。
从2013年1月至3月在尼耶里省总医院就诊的452例高血压患者的病历中提取有关血压、抗高血压药物使用和合并症的数据。血压控制充分定义为收缩压<140 mmHg(糖尿病高血压患者为<130 mmHg)和舒张压<90 mmHg(糖尿病高血压患者为<80 mmHg)。使用STATA 9(美国德克萨斯州StataCorp公司)输入和分析数据。
仅33.4%的患者血压在推荐范围内。在多变量分析中,使用钙通道阻滞剂与良好的血压控制显著相关(比值比,2.1;95%置信区间,1.4, 3.3)。另一方面,老年(≥60岁)、患有糖尿病以及使用三种或更多种抗高血压药物与良好血压控制的几率降低相关(比值比分别为0.64;95%置信区间,0.43;比值比为0.54;95%置信区间,0.36, 0.81;以及比值比为0.41;95%置信区间,0.26, 0.64)。
血压控制不佳是该地区高血压患者的一个重要公共卫生问题。老年患者、糖尿病患者以及接受多种药物治疗方案的患者血压控制不佳的风险更高,需要密切关注。