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[昏迷。创伤性脑损伤患者诱发电位的预后价值]

[Coma. The prognostic value of evoked potentials in patients after traumatic brain injury].

作者信息

Morgalla M H, Bauer J, Ritz R, Tatagiba M

机构信息

Neurochirurgische Klinik, Universität Tübingen.

出版信息

Anaesthesist. 2006 Jul;55(7):760-8. doi: 10.1007/s00101-006-1036-1.

DOI:10.1007/s00101-006-1036-1
PMID:16718461
Abstract

BACKGROUND

The prognosis after traumatic coma is often unclear. We investigated the prognostic value of somatosensory (SSEP) and early acoustic (EAEP) evoked potentials on comatose patients in the intensive care unit regarding long-term outcome. Different evaluation systems were investigated.

METHODS

This was a retrospective analysis of 100 patients. SSEP and EAEP were examined at different times and analysed according to the Riffel score. Combinations of the different types of potentials were evaluated regarding possible improvement of outcome prediction.

RESULTS

The positive predictive value of at least one missing peak V of the EAEP regarding a fatal prognosis was 83%. The negative predictive value of the EAEP was 96%. A good outcome (GOS 4+5) could be predicted by bilateral normal SSEP and EAEP with a positive predictive value of 98%.

CONCLUSIONS

Early evaluation of SSEP and EAEP allows reliable prognostic predictions regarding a later outcome in patients with severe traumatic brain injury and should therefore be used more often for intensive care patients.

摘要

背景

创伤性昏迷后的预后往往不明确。我们研究了体感诱发电位(SSEP)和早期听觉诱发电位(EAEP)对重症监护病房昏迷患者长期预后的预测价值。对不同的评估系统进行了研究。

方法

这是一项对100例患者的回顾性分析。在不同时间检查SSEP和EAEP,并根据里费尔评分进行分析。评估不同类型电位的组合对改善预后预测的可能性。

结果

EAEP至少一个V波峰缺失对致命预后的阳性预测值为83%。EAEP的阴性预测值为96%。双侧SSEP和EAEP正常可预测良好预后(GOS 4+5),阳性预测值为98%。

结论

对SSEP和EAEP的早期评估能够对重度创伤性脑损伤患者的后期预后做出可靠的预测,因此应更频繁地用于重症监护患者。

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本文引用的文献

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Predictive value of somatosensory evoked potentials for awakening from coma.体感诱发电位对昏迷苏醒的预测价值。
Crit Care Med. 2003 Mar;31(3):960-7. doi: 10.1097/01.CCM.0000053643.21751.3B.
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Prognostic value of SSEP in early aneurysm surgery after SAH in poor-grade patients.体感诱发电位在低级别蛛网膜下腔出血患者早期动脉瘤手术中的预后价值
Neurol Res. 2002 Dec;24(8):756-64. doi: 10.1179/016164102101200852.
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Improving the prediction of outcome in severe acute closed head injury by using discriminant function analysis of normal auditory brainstem response latencies and amplitudes.
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Outcome prediction in severe head injury: analyses of clinical prognostic factors.重型颅脑损伤的预后预测:临床预后因素分析
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Review of the use of somatosensory evoked potentials in the prediction of outcome after severe brain injury.体感诱发电位在预测重度脑损伤后预后中的应用综述。
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Auditory and somatosensory evoked potentials in coma following spontaneous cerebral hemorrhage: early prognosis and outcome.自发性脑出血后昏迷患者的听觉和体感诱发电位:早期预后与结局
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Early magnetic resonance imaging of brainstem lesions after severe head injury.重度颅脑损伤后脑干病变的早期磁共振成像
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[Usefulness and diagnostic value of evoked potentials in patients with neurologic diseases in postoperative intensive care].[诱发电位在术后重症监护神经疾病患者中的应用价值及诊断意义]
Anasthesiol Intensivmed Notfallmed Schmerzther. 1998 Jul;33(7):430-40. doi: 10.1055/s-2007-994280.
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Cerebral oxidative metabolism and evoked potential deterioration after severe brain injury: new evidence of early posttraumatic ischemia.严重脑损伤后脑氧化代谢及诱发电位恶化:创伤后早期缺血的新证据
Neurosurgery. 1998 May;42(5):1057-63; discussion 1063-4. doi: 10.1097/00006123-199805000-00060.