Marchand J C, Battin J
Ann Pediatr (Paris). 1989 Feb;36(2):101-4.
Among 15 children who were stung by hymenoptera, 5 underwent semi-rapid desensitization using the outpatient Molkhou method. This technique was well tolerated; desensitization was stopped when protective IgG levels measured by RIP (radioimmunoprecipitation) reached 50% and skin tests and RASTs became negative. In a comparable series of adults, however, discontinuation of the desensitization was considered only following satisfactory tolerance of an accidental or planned sting. In children, semi-rapid desensitization is very effective and has also been proposed for allergies to air borne allergens such as mites and pollens when increased doses are required to improve protection.
在15名被膜翅目昆虫蜇伤的儿童中,有5名采用门诊莫尔库法进行了半快速脱敏治疗。该技术耐受性良好;当通过放射免疫沉淀法(RIP)测得的保护性IgG水平达到50%且皮肤试验和放射性变应原吸附试验(RAST)呈阴性时,脱敏治疗停止。然而,在一组类似的成人病例中,只有在意外或计划性蜇刺耐受性良好后才考虑停止脱敏治疗。在儿童中,半快速脱敏治疗非常有效,当需要增加剂量以提高防护效果时,也有人提议将其用于对螨虫和花粉等空气传播过敏原的过敏治疗。