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[儿童对膜翅目昆虫毒液的过敏与脱敏]

[Allergy and desensitization to hymenoptera venom in children].

作者信息

Marchand J C, Battin J

出版信息

Ann Pediatr (Paris). 1989 Feb;36(2):101-4.

PMID:2930123
Abstract

Among 15 children who were stung by hymenoptera, 5 underwent semi-rapid desensitization using the outpatient Molkhou method. This technique was well tolerated; desensitization was stopped when protective IgG levels measured by RIP (radioimmunoprecipitation) reached 50% and skin tests and RASTs became negative. In a comparable series of adults, however, discontinuation of the desensitization was considered only following satisfactory tolerance of an accidental or planned sting. In children, semi-rapid desensitization is very effective and has also been proposed for allergies to air borne allergens such as mites and pollens when increased doses are required to improve protection.

摘要

在15名被膜翅目昆虫蜇伤的儿童中,有5名采用门诊莫尔库法进行了半快速脱敏治疗。该技术耐受性良好;当通过放射免疫沉淀法(RIP)测得的保护性IgG水平达到50%且皮肤试验和放射性变应原吸附试验(RAST)呈阴性时,脱敏治疗停止。然而,在一组类似的成人病例中,只有在意外或计划性蜇刺耐受性良好后才考虑停止脱敏治疗。在儿童中,半快速脱敏治疗非常有效,当需要增加剂量以提高防护效果时,也有人提议将其用于对螨虫和花粉等空气传播过敏原的过敏治疗。

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