Battin J, Guérin-Darmendrail V, Martin V
Ann Pediatr (Paris). 1989 Feb;36(2):132-5.
Report of overwhelming leukemia with meningeal involvement in a 13-year-old. Cytologic and ultrastructural examinations showed features of myelomonocytic leukemia with abnormal eosinophils. The karyotype showed pericentric inversion of chromosome 16. Although these findings establish the diagnosis of acute myelomonocytic leukemia with abnormal eosinophils (M4Eo), this case ran an exceptionally severe course and exhibited some unusual cytologic features.
一名13岁男性患伴有脑膜浸润的暴发性白血病的报告。细胞学和超微结构检查显示为伴有异常嗜酸性粒细胞的骨髓单核细胞白血病特征。核型显示16号染色体臂间倒位。尽管这些发现确立了伴有异常嗜酸性粒细胞的急性骨髓单核细胞白血病（M4Eo）的诊断，但该病例病程异常严重，并表现出一些不寻常的细胞学特征。
