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ICU 获得性肌无力:医学主权应归属任何专科医生吗?

ICU-acquired weakness: should medical sovereignty belong to any specialist?

机构信息

Unit of Neuro-Rehabilitation, Hospital IRCCS "Casa Sollievo della Sofferenza", Viale dei Cappuccini, 71013, San Giovanni Rotondo, FG, Italy.

出版信息

Crit Care. 2018 Jan 4;22(1):1. doi: 10.1186/s13054-017-1923-7.

DOI:10.1186/s13054-017-1923-7
PMID:29301549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5755267/
Abstract

ICU-acquired weakness (ICUAW), including critical illness polyneuropathy, critical illness myopathy, and critical illness polyneuropathy and myopathy, is a frequent disabling disorder in ICU subjects. Research has predominantly been performed by intensivists, whose efforts have permitted the diagnosis of ICUAW early during an ICU stay and understanding of several of the pathophysiological and clinical aspects of this disorder. Despite important progress, the therapeutic strategies are unsatisfactory and issues such as functional outcomes and long-term recovery remain unclear. Studies involving multiple specialists should be planned to better differentiate the ICUAW types and provide proper functional outcome measures and follow-up. A more strict collaboration among specialists interested in ICUAW, in particular physiatrists, is desirable to plan proper care pathways after ICU discharge and to better meet the health needs of subjects with ICUAW.

摘要

ICU 获得性肌无力(ICUAW),包括危重病性多发性神经病、危重病性肌病,以及危重病性多发性神经病和肌病,是 ICU 患者中一种常见的致残性疾病。研究主要由重症监护医师进行,他们的努力使得能够在 ICU 住院期间早期诊断 ICUAW,并了解该疾病的一些病理生理和临床方面。尽管取得了重要进展,但治疗策略仍不尽如人意,功能结局和长期恢复等问题仍不清楚。应计划涉及多个专科医生的研究,以更好地区分 ICUAW 类型,并提供适当的功能结局测量和随访。重症监护医师之间更严格的合作是必要的,特别是物理治疗师,以规划 ICU 出院后的适当护理途径,并更好地满足 ICUAW 患者的健康需求。

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本文引用的文献

1
Functional outcome of critical illness polyneuropathy in patients affected by severe brain injury.严重脑损伤患者危重病性多发性神经病的功能预后。
Eur J Phys Rehabil Med. 2017 Dec;53(6):910-919. doi: 10.23736/S1973-9087.17.04595-6. Epub 2017 Apr 14.
2
Diagnostic accuracy of quantitative neuromuscular ultrasound for the diagnosis of intensive care unit-acquired weakness: a cross-sectional observational study.定量神经肌肉超声诊断重症监护病房获得性肌无力的诊断准确性:一项横断面观察性研究。
Ann Intensive Care. 2017 Dec;7(1):40. doi: 10.1186/s13613-017-0263-8. Epub 2017 Apr 5.
3
The ICM research agenda on intensive care unit-acquired weakness.国际危重病医学学会关于重症加强治疗病房获得性衰弱的研究议程。
Intensive Care Med. 2017 Sep;43(9):1270-1281. doi: 10.1007/s00134-017-4757-5. Epub 2017 Mar 13.
4
Surviving critical illness: what is next? An expert consensus statement on physical rehabilitation after hospital discharge.危重症幸存者:接下来会怎样?关于出院后身体康复的专家共识声明。
Crit Care. 2016 Oct 29;20(1):354. doi: 10.1186/s13054-016-1508-x.
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Impaired Ca(2+) release contributes to muscle weakness in a rat model of critical illness myopathy.钙离子释放受损导致危重症性肌病大鼠模型出现肌肉无力。
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Critical illness polyneuropathy and myopathy 20 years later. No man's land? No, it is our land!20年后的危重病性多发性神经病和肌病。无人区?不,这是我们的领域!
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