Smith H C, Watson G H, Patel R G, Super M
Department of Cardiology, Royal Manchester Children's Hospital.
Arch Dis Child. 1989 Feb;64(2):196-200. doi: 10.1136/adc.64.2.196.
Echocardiography was performed in 60 people with tuberous sclerosis to ascertain the prevalence and course of cardiac rhabdomyomata at different ages. Twenty five (58%) of 43 children had tumours, but only three (18%) of 17 adults. The tumours tended to remain the same size through childhood. Only three infants were included but evidence from this and some published case reports suggest that the tumours tend to regress in early infancy and again in adolescence. The prevalence of tumours in young infants with tuberous sclerosis is likely to be considerably above 50%. As other signs of tuberous sclerosis are usually absent at this age echocardiography may afford the most useful diagnostic test in early infancy.
对60例结节性硬化症患者进行了超声心动图检查，以确定不同年龄阶段心脏横纹肌瘤的患病率和病程。43名儿童中有25名（58%）患有肿瘤，而17名成年人中只有3名（18%）患病。这些肿瘤在儿童期往往保持大小不变。仅纳入了3名婴儿，但据此及一些已发表的病例报告证据表明，这些肿瘤在婴儿早期及青春期往往会消退。结节性硬化症幼儿中肿瘤的患病率可能远高于50%。由于这个年龄段通常不存在结节性硬化症的其他体征，超声心动图可能是婴儿早期最有用的诊断检查。
