苏丹1型糖尿病成年患者的代谢控制目标：一项基于人群的研究。
Metabolic control targets in Sudanese adults with type 1 diabetes: A population-based study.
作者信息
Almobarak Ahmed O, Noor Sufian K, Elmadhoun Wadie M, Bushara Sarra O, Salim Reham S, Forawi Sittana A, Awadalla Heitham, Elwali Einas S, Ahmed Mohamed H
机构信息
Department of Pathology, Faculty of Medicine, Graduate College, University of Medical Sciences and Technology, Khartoum, Sudan.
Department of Medicine, Faculty of Medicine, Nile Valley University, Atbara, Sudan.
出版信息
J Family Med Prim Care. 2017 Apr-Jun;6(2):374-379. doi: 10.4103/jfmpc.jfmpc_359_16.
BACKGROUND
Type 1 diabetes is a challenging metabolic disorder for health authorities in Sudan. The objective of this study was to assess the level of glycemic control and to determine the prevalence of dyslipidemia and complications among individuals with type 1 diabetes in Sudan.
MATERIALS AND METHODS
Individuals with type 1 diabetes, who were having the disease for at least 1 year, were invited to participate in this study. Data were collected from two diabetes centers, in the Capital Khartoum and Atbara City, North of Sudan. Participants were interviewed using standardized pretested questionnaire to record medical history, sociodemographic data, and life style characteristics. Blood pressure, body mass index, and waist circumference were measured. Blood samples were taken for measurement of lipid profile and glycosylated hemoglobin.
RESULTS
A total of eighty individuals with type 1 diabetes volunteered to participate in this study, 37.5% of males and 62.5% of females. Majority of the patients were aged between 40 and 70 years old. There was poor glycemic control (glycosylated hemoglobin >7%), in 83.8%. Age and sex were significant factors associated with poor glycemic control in this cohort. High cholesterol, triglyceride, and low density lipoprotein were seen in 76.2%, 27.5%, and 48.8% of participants, respectively. Low high density lipoprotein was seen in 33.8%. Hypertension was determined in 21.3%. Peripheral neuropathy, visual impairment, diabetic foot, and myocardial infarction were seen in 50%, 48.8%, 18.8%, and 2.5% of patients, respectively.
CONCLUSION
Sudanese adults with type 1 diabetes have poor glycemic control, high prevalence of dyslipidemia, and long-term complications.
背景
1型糖尿病对苏丹的卫生当局来说是一种具有挑战性的代谢紊乱疾病。本研究的目的是评估血糖控制水平，并确定苏丹1型糖尿病患者中血脂异常和并发症的患病率。
材料与方法
邀请患有1型糖尿病至少1年的个体参与本研究。数据从苏丹首都喀土穆和北部阿特巴拉市的两个糖尿病中心收集。使用经过预测试的标准化问卷对参与者进行访谈，以记录病史、社会人口统计学数据和生活方式特征。测量血压、体重指数和腰围。采集血样以测量血脂谱和糖化血红蛋白。
结果
共有80名1型糖尿病患者自愿参与本研究，其中男性占37.5%，女性占62.5%。大多数患者年龄在40至70岁之间。血糖控制不佳（糖化血红蛋白>7%）的患者占83.8%。在该队列中，年龄和性别是与血糖控制不佳相关的重要因素。分别有76.2%、27.5%和48.8%的参与者出现高胆固醇、高甘油三酯和低密度脂蛋白升高。33.8%的参与者出现高密度脂蛋白降低。21.3%的患者被诊断为高血压。分别有50%、48.8%、18.8%和2.5%的患者出现周围神经病变、视力损害、糖尿病足和心肌梗死。
结论
苏丹成年1型糖尿病患者血糖控制不佳，血脂异常患病率高，且存在长期并发症。
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