Awadalla Heitham, Noor Sufian K, Elmadhoun Wadie M, Bushara Sarra O, Almobarak Ahmed O, Sulaiman Amel Abdalrhim, Ahmed Mohamed H
Department of community Medicine, Faculty of Medicine, University of Khartoum, Sudan.
Department of Medicine, Nile Valley University, Atbara, Sudan.
Diabetes Metab Syndr. 2018 Nov;12(6):961-964. doi: 10.1016/j.dsx.2018.06.004. Epub 2018 Jun 6.
Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. Dyslipidemia is a major complication of diabetes and an important risk factor for cardiovascular disease (CVD). The objective of this study was to determine the prevalence of dyslipidemia and its co-relation with the glycemic control in individuals with diabetes in River Nile State, Sudan.
Individuals with diabetes attended, Naserudin Karamalla Diabetic (NKDM) Centre, in Atbara teaching hospital during study period, who volunteered to participate were included. Only those on treatment for DM for at least one year were included. Venous samples were collected for cholesterol, triglycerides, HDL, LDL, blood glucose and Glycosylated hemoglobin. Participants were interviewed using standardized pretested questionnaire to record medical history and sociodemographic characteristics. Blood pressure, body mass index (BMI) and waist circumference were measured.
A total of 188 individuals were included. The mean age was 49.5 + 13.9 and (128) 68.1% were females. Most patients were having DM for at least 3-5 years 69 (36.7%). Poor diabetes control (HbA1c >7) was recorded in 87.2%, hypercholesterolemia, hypertriglyceridemia and high LDL were identified in 36.6%, 27.7% and 26.6% respectively. In addition, HDL was low in 61.2% of patients.
Low HDL is a prominent feature in two thirds of individuals with diabetes, while high cholesterol and high triglyceride were seen in over one quarter.
糖尿病（DM）是苏丹的一个主要健康问题，也是发病和死亡的主要原因。血脂异常是糖尿病的主要并发症，也是心血管疾病（CVD）的重要危险因素。本研究的目的是确定苏丹尼罗河州糖尿病患者血脂异常的患病率及其与血糖控制的相关性。
在研究期间，前往阿特巴拉教学医院纳瑟鲁丁·卡拉马拉糖尿病（NKDM）中心就诊的糖尿病患者，自愿参与者被纳入研究。仅纳入接受糖尿病治疗至少一年的患者。采集静脉血样检测胆固醇、甘油三酯、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、血糖和糖化血红蛋白。使用标准化的预测试问卷对参与者进行访谈，以记录病史和社会人口学特征。测量血压、体重指数（BMI）和腰围。
共纳入188名个体。平均年龄为49.5±13.9岁，女性128名（68.1%）。大多数患者患糖尿病至少3 - 5年，共69名（36.7%）。87.2%的患者糖尿病控制不佳（糖化血红蛋白>7），高胆固醇血症、高甘油三酯血症和高LDL的检出率分别为36.6%、27.7%和26.6%。此外，61.2%的患者HDL水平较低。
三分之二的糖尿病患者存在HDL水平低的显著特征，而超过四分之一的患者存在高胆固醇和高甘油三酯。
