苏丹糖尿病患者中风的患病率及危险因素：横断面调查
The prevalence and risk factors of stroke among Sudanese individuals with diabetes: Cross-sectional survey.
作者信息
Almobarak Ahmed Omer, Badi Safaa, Elmadhoun Wadie M, Tahir Hanan, Ahmed Mohamed H
机构信息
Department of Pathology, Faculty of Medicine, University of Medical Sciences and Technology, Omdurman, Khartoum, Sudan.
Delta College of Science and Technology, Faculty of Pharmacy, Omdurman Islamic University, Omdurman, Khartoum, Sudan.
出版信息
Brain Circ. 2020 Feb 18;6(1):26-30. doi: 10.4103/bc.bc_15_19. eCollection 2020 Jan-Mar.
INTRODUCTION
Diabetes complications in Sudan were increasing at an alarming rate. The aim of this study was to assess the prevalence of stroke among Sudanese individuals with diabetes.
METHODOLOGY
This cross-sectional study recruited 283 individuals with diabetes from three diabetes centers in Sudan. Data were collected using a standardized pretested questionnaire, and data were analyzed using Chi-square and logistic regression analysis.
RESULTS
The average age of participants was 51 (±12 standard deviation) and 35% were aged between 51 and 60 years. Females were 66.8%, and most of the participants (73.9%) were from urban areas and 66.1% received formal education between primary school and university. Body mass index (BMI) classification showed that 34.3% were obese, 31.8% overweight, and 30.4% normal BMI. Diabetes for 1-5 years were observed in 71.7% and for more than 10 years (12%). The majority, i.e., 94.3% had type 2 diabetes mellitus while only 5.7% had type 1. Only one-third of the participants were able to achieve glycosylated hemoglobin (HbA1c) target for diabetes control. The prevalence of cerebrovascular accident (CVA) was 2.5%, hypertension (HTN) was 20%, ischemic heart disease 3.2%, and neuropathy was 45.6%. Chi-square test showed significant association between HbA1c, serum creatinine, total cholesterol, triglyceride, low density lipoprotein, high density lipoprotein level, and the presence of CVA. Logistic regression analysis showed HbA1c, and the duration of diabetes are significantly associated with the presence of CVA ( = 0.010, 0.014).
CONCLUSION
The prevalence of stroke among Sudanese individuals with diabetes was around 2.5%. The main risk factors were HbA1c, HTN, and duration of diabetes.
引言
苏丹糖尿病并发症的发生率正以惊人的速度上升。本研究的目的是评估苏丹糖尿病患者中中风的患病率。
方法
这项横断面研究从苏丹的三个糖尿病中心招募了283名糖尿病患者。使用经过预测试的标准化问卷收集数据，并采用卡方检验和逻辑回归分析进行数据分析。
结果
参与者的平均年龄为51岁（标准差±12），35%的年龄在51至60岁之间。女性占66.8%，大多数参与者（73.9%）来自城市地区，66.1%接受过小学至大学的正规教育。体重指数（BMI）分类显示，34.3%为肥胖，31.8%超重，30.4%的BMI正常。71.7%的患者糖尿病病程为1至5年，超过10年的占12%。大多数患者（94.3%）患有2型糖尿病，只有5.7%患有1型糖尿病。只有三分之一的参与者能够达到糖尿病控制的糖化血红蛋白（HbA1c）目标。脑血管意外（CVA）的患病率为2.5%，高血压（HTN）为20%，缺血性心脏病为3.2%，神经病变为45.6%。卡方检验显示HbA1c、血清肌酐、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白水平与CVA的存在之间存在显著关联。逻辑回归分析显示HbA1c和糖尿病病程与CVA的存在显著相关（P = 0.010，0.014）。
结论
苏丹糖尿病患者中中风的患病率约为2.5%。主要危险因素是HbA1c、HTN和糖尿病病程。
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