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苏丹2型糖尿病患者的血糖控制:基于人群的研究。

Glycaemic control in Sudanese individuals with type 2 diabetes: Population based study.

作者信息

Noor Sufian K, Elmadhoun Wadie M, Bushara Sarra O, Almobarak Ahmed O, Salim Reham S, Forawi Sittana A, Awadallah Heitham, Elwali Einas S, Ahmed Mohamed H

机构信息

Department of Medicine, Nile Valley University, Atbara, Sudan.

Department of Pathology, Nile Valley University, Atbara, Sudan.

出版信息

Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S147-S151. doi: 10.1016/j.dsx.2016.12.024. Epub 2016 Dec 27.

DOI:10.1016/j.dsx.2016.12.024
PMID:28034691
Abstract

BACKGROUND

Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. The objective of this study was to determine the prevalence of glycaemic control among individuals with type 2 diabetes across different cities in Sudan.

METHODS

Individuals with type 2 diabetes attending selected diabetes centres in Sudan, who had been on treatment for DM for at least one year and volunteered to participate were included. Participants were interviewed using standardized pretested questionnaire to record medical history, sociodemographic and life style characteristics. Lipid profile and glycosylated hemoglobin were tested by calibrated laboratory methods. Blood pressure, Body mass index (BMI) and waist circumference were measured. Chi squared and logistic regression were used as statistical methods.

RESULTS

A total of 387 individuals with T2DM were included in this study (50.4% males and 49.6% females). The glycemic control indicator (HbAIc>7) was poor in 85% of patients. Factors associated with poor glycemic control were prolonged duration of diabetes (p=0.03), high plasma triglyceride (p=0.02), low high density lipoprotein (HDL) level (p=0.04) and low glomerular filtration rate (GFR) (P=0.01). Logistic regression analysis showed that low GFR is independent factor with poor diabetes control.

CONCLUSION

High prevalence of uncontrolled diabetes (85%) is noted in Sudanese individuals with type 2 diabetes.

摘要

背景

糖尿病(DM)是苏丹的一个主要健康问题,也是发病和死亡的主要原因。本研究的目的是确定苏丹不同城市2型糖尿病患者的血糖控制患病率。

方法

纳入在苏丹选定糖尿病中心就诊、接受糖尿病治疗至少一年且自愿参与的2型糖尿病患者。使用标准化的预测试问卷对参与者进行访谈,以记录病史、社会人口统计学和生活方式特征。通过校准的实验室方法检测血脂谱和糖化血红蛋白。测量血压、体重指数(BMI)和腰围。采用卡方检验和逻辑回归作为统计方法。

结果

本研究共纳入387例2型糖尿病患者(男性50.4%,女性49.6%)。85%的患者血糖控制指标(糖化血红蛋白>7)较差。与血糖控制不佳相关的因素包括糖尿病病程延长(p=0.03)、血浆甘油三酯升高(p=0.02)、高密度脂蛋白(HDL)水平降低(p=0.04)和肾小球滤过率(GFR)降低(P=0.01)。逻辑回归分析表明,低GFR是糖尿病控制不佳的独立因素。

结论

苏丹2型糖尿病患者中未控制糖尿病的患病率较高(85%)。

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