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印度南部海得拉巴大都市城市老年人口中维生素D缺乏症的患病率及其相关因素。

Prevalence of vitamin D deficiency and its associated factors among the urban elderly population in Hyderabad metropolitan city, South India.

作者信息

Suryanarayana Palla, Arlappa Nimmathota, Sai Santhosh Vadakattu, Balakrishna Nagalla, Lakshmi Rajkumar Pondey, Prasad Undrajavarapu, Raju Banavath Bhoja, Shivakeseva Kommula, Divya Shoshanni Kondru, Seshacharyulu Madabushi, Geddam Jagjeevan Babu, Prasanthi Prabhakaran Sobhana, Ananthan Rajendran

机构信息

a Lipid Chemistry Division , National Institute of Nutrition , Hyderabad , India.

b Field Division , National Institute of Nutrition , Hyderabad , India.

出版信息

Ann Hum Biol. 2018 Mar;45(2):133-139. doi: 10.1080/03014460.2018.1425479. Epub 2018 Feb 15.

DOI:10.1080/03014460.2018.1425479
PMID:29307228
Abstract

BACKGROUND

Deficiency of vitamin D has been associated with various health conditions. However, vitamin D deficiency (VDD) and factors associated with VDD are not well studied, especially among the urban elderly population of India.

AIM

To assess the prevalence of VDD and its associated factors among the urban free-living elderly population in Hyderabad.

SUBJECTS AND METHODS

A community-based cross-sectional study was conducted among 298 urban elderly (≥60 years) by adapting a random sampling procedure. Demographic particulars were collected. Blood pressure and anthropometric measurements were recorded using standard equipment. Fasting glucose, lipid profile and 25-hydroxy vitamin D [25(OH) D] were estimated in plasma samples.

RESULTS

The mean ± SE plasma vitamin D and the prevalence of VDD among the urban elderly population were 19.3 ± 0.54 (ng/ml) and 56.3%, respectively. The prevalence of VDD was significantly associated with education, high body mass index (BMI), hypertension (HT) and metabolic syndrome (MS). Multiple logistic regression analysis revealed HT as a significant predictor of vitamin D deficiency and the risk of VDD was double among the elderly with hypertension.

CONCLUSIONS

The prevalence of VDD was high among the urban elderly population in the south Indian city of Hyderabad. High BMI, MS, HT and education are significant associated factors of VDD.

摘要

背景

维生素D缺乏与多种健康状况相关。然而,维生素D缺乏(VDD)及其相关因素尚未得到充分研究,尤其是在印度城市老年人群中。

目的

评估印度海得拉巴市城市自由生活老年人中VDD的患病率及其相关因素。

对象与方法

采用随机抽样程序,对298名城市老年人(≥60岁)进行了一项基于社区的横断面研究。收集了人口统计学详情。使用标准设备记录血压和人体测量数据。对血浆样本进行空腹血糖、血脂谱和25-羟基维生素D [25(OH)D]测定。

结果

城市老年人群血浆维生素D均值±标准误为19.3±0.54(ng/ml),VDD患病率为56.3%。VDD患病率与教育程度、高体重指数(BMI)、高血压(HT)和代谢综合征(MS)显著相关。多因素logistic回归分析显示HT是维生素D缺乏的重要预测因素,高血压老年人VDD风险增加一倍。

结论

在印度南部城市海得拉巴的城市老年人群中,VDD患病率较高。高BMI、MS、HT和教育程度是VDD的重要相关因素。

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