ECMO Program, Children's Hospital of Philadelphia, Philadelphia, PA.
ECMO Program, Children's Hospital of Philadelphia, Philadelphia, PA; Division of General, Thoracic, and Fetal Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Semin Perinatol. 2018 Mar;42(2):89-95. doi: 10.1053/j.semperi.2017.12.004. Epub 2018 Jan 4.
Extracorporeal membrane oxygenation (ECMO) for neonates is applied routinely at major children's hospitals around the world. While the practice seems routine, the peculiar physiology of the small human imposes particular constraints on selection of equipment, performance of the circuit, and risks to the child. The physiology of small patients and physics of circuit elements leave many areas opaque and far from optimal, but still allow assembly of a set of useful heuristics for good practice. Here, we examine individual mechanical components of the ECMO circuit with attention to selection, pitfalls, and peculiarities of each when applied to the neonate.
体外膜肺氧合（ECMO）在全球各大儿童医院常规应用于新生儿。尽管该操作看似常规，但小儿特殊的生理学特性对设备的选择、回路的性能以及患儿的风险都提出了特殊的限制。小患者的生理学特性和回路元件的物理学特性使得许多方面不透明且远非最佳，但仍允许为良好的实践组装一组有用的启发式方法。在这里，我们检查 ECMO 回路的各个机械部件，重点关注在应用于新生儿时每个部件的选择、陷阱和特点。
