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长效棘白菌素CD101对耳念珠菌临床分离株的活性。

Activity of CD101, a long-acting echinocandin, against clinical isolates of Candida auris.

作者信息

Berkow Elizabeth L, Lockhart Shawn R

机构信息

Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA.

Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA.

出版信息

Diagn Microbiol Infect Dis. 2018 Mar;90(3):196-197. doi: 10.1016/j.diagmicrobio.2017.10.021. Epub 2017 Nov 7.

DOI:10.1016/j.diagmicrobio.2017.10.021
PMID:29307565
Abstract

CD101 is a new echinocandin with a prolonged half-life. CD101 was tested by broth microdilution against 100 isolates of the emerging yeast Candida auris. It showed activity against most isolates, including some that were resistant to other echinocandins.

摘要

CD101是一种半衰期延长的新型棘白菌素。采用肉汤微量稀释法对100株新兴的耳道假丝酵母菌分离株进行了CD101测试。它对大多数分离株具有活性，包括一些对其他棘白菌素耐药的分离株。

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