Corona Pablo S, Lung Mayli, Rodriguez-Pardo Dolors, Pigrau Carles, Soldado Francisco, Amat Carles, Carrera Luis
Septic and Reconstructive Surgery Unit, Orthopedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.
Microbiology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Anaerobe. 2018 Feb;49:116-120. doi: 10.1016/j.anaerobe.2017.12.010. Epub 2018 Jan 5.
Fusobacterium nucleatum is an obligately anaerobic gram-negative rod, a component of the microbiome of the oropharynx and the gastrointestinal and urogenital tracts, causing an array of human infections which often include periodontal pathologies. As far as we know, there are no previous publications about acute periprosthetic joint infection due to Fusobacterium sp.; we report the first case in the medical literature of an aggressive, acute knee prosthetic infection due to F. nucleatum in a non-immunocompromised patient, unsuccessfully treated with a DAIR approach (Debridement + Antibiotics + Implant Retention).
具核梭杆菌是一种专性厌氧的革兰氏阴性杆菌，是口咽、胃肠道和泌尿生殖道微生物群的组成部分，可引发一系列人类感染，其中常包括牙周疾病。据我们所知，此前尚无关于梭杆菌属导致急性人工关节周围感染的相关报道；我们报告了医学文献中的首例病例，一名非免疫功能低下患者因具核梭杆菌引发侵袭性急性膝关节假体感染，采用清创术+抗生素+保留假体（DAIR）方法治疗未成功。
