Carvalho Karla Maria, Sawant Poonam Ramnath, Dhupar Anita, Spadigam Anita
Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India.
Int J Appl Basic Med Res. 2017 Oct-Dec;7(4):278-280. doi: 10.4103/ijabmr.IJABMR_417_16.
India is considered to be the oral cancer capital of the world. Oral squamous cell carcinoma is a multifactorial disease with tobacco and alcohol being considered major risk factors. However, there is a growing incidence of nonhabit (i.e., the absence of tobacco or alcohol) associated oral cancer. Difference is noted in demographics, site predilection, grade, and stage while comparing habit associated and nonhabit associated oral carcinoma. This warrants a need for a greater understanding of carcinogenesis without a known carcinogen. This case adds to the sparse existing scientific literature on oral cancer in nonhabitués and reviews the possible etiopathogenic mechanisms underlying the disease process.
印度被认为是世界口腔癌之都。口腔鳞状细胞癌是一种多因素疾病,烟草和酒精被视为主要危险因素。然而,与无习惯(即不吸烟或不饮酒)相关的口腔癌发病率正在上升。在比较有习惯相关和无习惯相关的口腔癌时,在人口统计学、部位偏好、分级和分期方面存在差异。这就需要更深入地了解无已知致癌物情况下的致癌作用。本病例补充了关于非习惯人群口腔癌的稀少现有科学文献,并回顾了该疾病过程潜在的可能病因发病机制。