Esteves Sol, Ramirez Romero Diana Andrea, Torralva Teresa, Martínez Cuitiño Macarena, Herndon Shannon, Couto Blas, Ibañez Agustín, Manes Facundo, Roca María
a Neuropsychological Research Laboratory, Institute of Cognitive and Translational Neuroscience (INCyT), INECO Foundation, Favaloro University, CONICET , Buenos Aires , Argentina.
b Department of Psychiatry, School of Medicine, University of North Carolina Chapel Hill , Chapel Hill , USA.
Neurocase. 2018 Feb;24(1):16-30. doi: 10.1080/13554794.2017.1421667. Epub 2018 Jan 8.
Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome characterized by initial predominant visuoperceptual deficits followed by a progressive decline in other cognitive functions. This syndrome has not been as thoroughly described as other dementias, particularly from a neuropsychological evolution perspective with only a few studies describing the evolution of its cognitive progression. In this investigation we review the literature on this rare condition and we perform a 7-year neuropsychological and neuroradiological follow-up of a 64-year-old man with PCA. The subject's deficits initially appeared in his visuoperceptual skills with later affectation appearing in language and other cognitive functions, this being coherent with the patient's parieto-temporal atrophy evolution.
后皮质萎缩（PCA）是一种罕见的神经退行性综合征，其特征是最初主要表现为视觉感知缺陷，随后其他认知功能逐渐衰退。与其他痴呆症相比，这种综合征尚未得到充分描述，特别是从神经心理学演变的角度来看，只有少数研究描述了其认知进展的演变。在本研究中，我们回顾了关于这种罕见病症的文献，并对一名患有PCA的64岁男性进行了为期7年的神经心理学和神经放射学随访。该患者的缺陷最初出现在视觉感知技能方面，随后语言和其他认知功能也受到影响，这与患者顶颞叶萎缩的演变情况一致。
