Carroll Paul, Henshaw Robert M, Garwood Caitlin, Raspovic Katherine, Kumar Dhruv
Division of Podiatric Surgery, Center for Wound Healing, MedStar Georgetown University Hospital, Washington, DC (PC).
MedStar Washington Hospital Center, MedStar Georgetown Orthopedic Institute, Georgetown University School of Medicine, Washington, DC (RMH).
Foot Ankle Spec. 2018 Apr;11(2):168-176. doi: 10.1177/1938640017751184. Epub 2018 Jan 9.
Plantar fibromatosis (morbus Ledderhose), an extra-abdominal desmoid tumor of the plantar foot, is a rare benign hyperproliferative disorder of the plantar fascia with an unknown etiology. The main clinical characteristics include slow growing nodules on the medial and central bands of the plantar fascia, which may become painful and negatively affect ambulation. Most established conservative therapies today target symptomatic relief. As symptoms progress, therapies such as injections, shockwave ablation, radiation, and/or surgery may be required. This review aims to provide insight into the pathophysiology of this condition in addition to detailing current and investigational therapies for this disorder. Many therapies have been proven in similar conditions, which could lead to promising treatment options for plantar fibromatosis.
Level V: Expert opinion.
足底纤维瘤病（Ledderhose病）是足底的一种腹外硬纤维瘤，是一种病因不明的足底筋膜罕见良性增殖性疾病。主要临床特征包括足底筋膜内侧和中央束带处生长缓慢的结节，这些结节可能会疼痛并对行走产生负面影响。目前大多数既定的保守治疗旨在缓解症状。随着症状进展，可能需要注射、冲击波消融、放射治疗和/或手术等治疗方法。本综述旨在深入了解该疾病的病理生理学，同时详细介绍该疾病的当前治疗方法和研究性治疗方法。许多治疗方法已在类似病症中得到验证，这可能为足底纤维瘤病带来有前景的治疗选择。
V级：专家意见。
