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肝移植后心力衰竭的诊断与治疗挑战:病例系列

Diagnostic and therapeutic challenge of heart failure after liver transplant: Case series.

作者信息

Tandon Manish, Karna Sunaina Tejpal, Pandey Chandra Kant, Chaturvedi Ravindra

机构信息

Institute of Liver and Biliary Sciences, New Delhi 110070, India.

出版信息

World J Hepatol. 2017 Nov 28;9(33):1253-1260. doi: 10.4254/wjh.v9.i33.1253.

DOI:10.4254/wjh.v9.i33.1253
PMID:29312528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5745586/
Abstract

Heart failure (HF) following liver transplant (LT) surgery is a distinct clinical entity with high mortality. It is known to occur in absence of obvious risk factors. No preoperative workup including electrocardiogram, echocardiography at rest and on stress, reasonably prognosticates the risk. In patients of chronic liver disease, cirrhotic cardiomyopathy, alcoholic cardiomyopathy, and stress induced cardiomyopathy have each been implicated as a cause for HF after LT. However distinguishing one etiology from another not only is difficult, several etiologies may possibly coexist in a given patient. Diagnostic dilemma is further compounded by the fact that presentation and management of HF irrespective of the possible underlying cause, remains the same. In this case series, 6 cases are presented and in the light of existing literature modification in the preoperative workup are suggested.

摘要

肝移植(LT)手术后发生的心力衰竭(HF)是一种死亡率很高的独特临床实体。已知其在没有明显危险因素的情况下发生。包括心电图、静息和负荷超声心动图在内的术前检查均无法合理预测这种风险。在慢性肝病患者中,肝硬化性心肌病、酒精性心肌病和应激性心肌病都被认为是肝移植后发生心力衰竭的原因。然而,区分一种病因与另一种病因不仅困难,而且在特定患者中几种病因可能同时存在。由于无论潜在病因如何,心力衰竭的表现和管理都相同,这进一步加剧了诊断困境。在本病例系列中,报告了6例病例,并根据现有文献对术前检查提出了改进建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba41/5745586/3f5de39704dc/WJH-9-1253-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba41/5745586/3f5de39704dc/WJH-9-1253-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba41/5745586/3f5de39704dc/WJH-9-1253-g001.jpg

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本文引用的文献

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Post-operative hypertension, a surrogate marker of the graft function and predictor of survival in living donor liver transplant recipients: A retrospective study.
Indian J Anaesth. 2016 Jul;60(7):463-9. doi: 10.4103/0019-5049.186016.
2
Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.Takotsubo(应激性)心肌病的临床特征和转归。
N Engl J Med. 2015 Sep 3;373(10):929-38. doi: 10.1056/NEJMoa1406761.
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Novel approach for heart failure treatment after liver transplantation.肝移植后心力衰竭治疗的新方法。
未知的边缘:肝移植术后重症监护
J Clin Med. 2022 Jul 12;11(14):4036. doi: 10.3390/jcm11144036.
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Hepatic Artery Thrombosis and Takotsubo Syndrome After Liver Transplantation - Which Came First?肝移植术后肝动脉血栓形成和 Takotsubo 综合征——哪个先来?
Am J Case Rep. 2020 Apr 14;21:e920263. doi: 10.12659/AJCR.920263.
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Cardiac Imaging in Liver Transplantation Candidates: Current Knowledge and Future Perspectives.肝移植候选者的心脏成像:当前认知与未来展望
J Clin Med. 2019 Dec 3;8(12):2132. doi: 10.3390/jcm8122132.
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Leucocytosis before liver transplant, source could be hiding in heart: Case report.肝移植前白细胞增多症,病因可能隐匿于心脏:病例报告
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Transplantation. 2015 Apr;99(4):873-8. doi: 10.1097/TP.0000000000000387.
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Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes.非心脏手术后心肌损伤:一项大型国际前瞻性队列研究,确立了诊断标准、特征、预测因素和 30 天结局。
Anesthesiology. 2014 Mar;120(3):564-78. doi: 10.1097/ALN.0000000000000113.
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Early-onset and late-onset heart failure after liver transplantation.肝移植术后的早发型和迟发型心力衰竭
Liver Transpl. 2014 Jan;20(1):122. doi: 10.1002/lt.23760. Epub 2013 Nov 21.
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Liver Transpl. 2013 Jul;19(7):701-10. doi: 10.1002/lt.23654. Epub 2013 Jun 3.
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Characteristics and short-term prognosis of perioperative myocardial infarction in patients undergoing noncardiac surgery: a cohort study.非心脏手术围术期心肌梗死患者的特征及短期预后:一项队列研究。
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