Testori Alberto, Meroni Stefano, Voulaz Emanuele, Alloisio Marco, De Sanctis Rita, Bossi Paola, Cariboni Umberto, De Simone Matilde, Cioffi Ugo
General and Thoracic Surgery, Humanitas Research Hospital, Rozzano (Milan), Italy.
Division of Breast Radiology, European Institute of Oncology, Milan, Italy.
J Thorac Dis. 2017 Dec;9(12):E1054-E1059. doi: 10.21037/jtd.2017.10.98.
Radiological and histological features of breast leiomyosarcoma can mimic a wide variety of other breast lesions, such as mesenchymal tumors, breast lymphomas, poorly differentiated carcinomas and metaplastic breast carcinomas. The authors present the case of a 62-year-old woman with a primary breast leiomyosarcoma with synchronous ipsilateral lung adenocarcinoma. The latter was an incidental finding during pre-surgical staging examinations. Clinicopathological, immunophenotypic and imaging features cancer are described. A brief review of the literature on imaging findings and management of breast leiomyosarcoma is presented. The authors discuss the differential diagnoses in breast imaging and of the extra-mammary incidental findings. Surgical resection remains the cornerstone of treatment, while radiation therapy and chemotherapy remain to be defined on a single-patient basis.
乳腺平滑肌肉瘤的放射学和组织学特征可模仿多种其他乳腺病变，如间叶性肿瘤、乳腺淋巴瘤、低分化癌和化生性乳腺癌。作者报告了一例62岁女性原发性乳腺平滑肌肉瘤合并同侧肺腺癌的病例。后者是术前分期检查时偶然发现的。描述了其临床病理、免疫表型和影像学特征。对乳腺平滑肌肉瘤的影像学表现和治疗的文献进行了简要回顾。作者讨论了乳腺影像学中的鉴别诊断以及乳腺外偶然发现的情况。手术切除仍然是治疗的基石，而放疗和化疗仍需根据个体情况确定。
