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本文引用的文献

1
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.肝细胞癌的综合与整合基因组特征分析
Cell. 2017 Jun 15;169(7):1327-1341.e23. doi: 10.1016/j.cell.2017.05.046.
2
Integrative Genomic Analysis Identifies the Core Transcriptional Hallmarks of Human Hepatocellular Carcinoma.整合基因组分析确定人类肝细胞癌的核心转录特征
Cancer Res. 2016 Nov 1;76(21):6374-6381. doi: 10.1158/0008-5472.CAN-16-1559. Epub 2016 Sep 12.
3
Genetic profiling of hepatocellular carcinoma using next-generation sequencing.使用下一代测序技术对肝细胞癌进行基因谱分析。
J Hepatol. 2016 Nov;65(5):1031-1042. doi: 10.1016/j.jhep.2016.05.035. Epub 2016 Jun 2.
4
Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression.CTNNB1 基因突变的表型-基因型相关性揭示了与肝肿瘤进展相关的不同 β-连环蛋白活性。
Hepatology. 2016 Dec;64(6):2047-2061. doi: 10.1002/hep.28638. Epub 2016 Jun 11.
5
Long Noncoding RNAs in Cancer Pathways.癌症通路中的长链非编码RNA
Cancer Cell. 2016 Apr 11;29(4):452-463. doi: 10.1016/j.ccell.2016.03.010.
6
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.肝细胞癌的遗传景观和生物标志物。
Gastroenterology. 2015 Oct;149(5):1226-1239.e4. doi: 10.1053/j.gastro.2015.05.061. Epub 2015 Jun 20.
7
Advances in targeted therapies for hepatocellular carcinoma in the genomic era.基因组时代肝细胞癌的靶向治疗进展。
Nat Rev Clin Oncol. 2015 Jul;12(7):408-24. doi: 10.1038/nrclinonc.2015.103. Epub 2015 Jun 9.
8
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.肝细胞癌的外显子组测序鉴定出新的突变特征和潜在治疗靶点。
Nat Genet. 2015 May;47(5):505-511. doi: 10.1038/ng.3252. Epub 2015 Mar 30.
9
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.跨种族肝细胞癌基因组的突变特征。
Nat Genet. 2014 Dec;46(12):1267-73. doi: 10.1038/ng.3126. Epub 2014 Nov 2.
10
Combined hepatocellular-cholangiocarcinomas exhibit progenitor features and activation of Wnt and TGFβ signaling pathways.混合型肝细胞癌-胆管细胞癌具有祖细胞特征，并激活了 Wnt 和 TGFβ 信号通路。
Carcinogenesis. 2012 Sep;33(9):1791-6. doi: 10.1093/carcin/bgs208. Epub 2012 Jun 13.

Landscape of genomic alterations in hepatocellular carcinoma: current knowledge and perspectives for targeted therapies.

作者信息

Bévant Kévin, Coulouarn Cédric

机构信息

Inserm, Inra, Univ Rennes, UMR 1241, Nutrition Metabolisms and Cancer, Rennes, France.

出版信息

Hepatobiliary Surg Nutr. 2017 Dec;6(6):404-407. doi: 10.21037/hbsn.2017.10.02.

DOI:10.21037/hbsn.2017.10.02
PMID:29312976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5756761/
Abstract
摘要