Egorova Ksenia S, Ananikov Valentine P
Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47, Moscow, 119991, Russia.
Biophys Rev. 2018 Jun;10(3):881-900. doi: 10.1007/s12551-017-0389-9. Epub 2018 Jan 8.
Comparison of chemical catalysis by metal complexes, enzymatic catalysis and whole-cell biocatalysis shows well-addressed advantages of the latter approach. However, a critical limitation in the practical applications originates from the high sensitivity of microorganisms to the toxic effects of organic solvents. In the present review, we consider toxic solvent properties of ionic liquid/water systems towards the development of efficient applications in practical organic transformations.
金属配合物的化学催化、酶催化和全细胞生物催化的比较显示了后一种方法具有充分体现的优势。然而，实际应用中的一个关键限制源于微生物对有机溶剂毒性作用的高度敏感性。在本综述中，我们考虑离子液体/水体系的有毒溶剂性质，以推动其在实际有机转化中的高效应用发展。
