诺肽普对培养的大鼠海马切片神经元细胞内钙动力学的影响。
Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices.
作者信息
Kolbaev S N, Aleksandrova O P, Sharonova I N, Skrebitsky V G
机构信息
Research Center of Neurology, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2018 Jan;164(3):330-333. doi: 10.1007/s10517-018-3983-3. Epub 2018 Jan 8.
PMID:29313229
Abstract
A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices. In contrast, the drug exerted no significant effect on intracellular calcium concentration and its dynamics in neurons of hippocampal CA1 pyramidal layer.
摘要
一种具有神经保护和益智作用的药物诺肽普汀增加了培养的大鼠海马切片CA1放射层神经元中自发钙瞬变的频率。相比之下，该药物对海马CA1锥体层神经元的细胞内钙浓度及其动态没有显著影响。
Zotero 插件