Deng Hua, Zhang Ying, Yu Hongtao
a Department of Chemistry, School of Computer, Mathematical and Natural Sciences , Morgan State University , Baltimore , Maryland , USA.
b Department of Chemistry and Biochemistry, College of Science, Engineering and Technology , Jackson State University , Jackson , Mississippi , USA.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2018 Jan 2;36(1):1-20. doi: 10.1080/10590501.2018.1418792. Epub 2018 Jan 9.
Nanoparticles are used widely in our lives, but the understanding of their impacts on human and environmental health is still limited, at least due in part to the fact that nanoparticles are mixtures. This review describes that "nanotoxicity" is actually a test of the overall effect of a nanoparticle mixture: starting materials for nanoparticle preparation, surface coating agents, surface reaction-generated species, and transformed byproducts of the nanoparticle in biological and environmental media, as well as variations of the intrinsic nanoparticle structures.
纳米颗粒在我们的生活中被广泛使用，但对于它们对人类和环境健康影响的理解仍然有限，至少部分原因是纳米颗粒是混合物。这篇综述描述了“纳米毒性”实际上是对纳米颗粒混合物整体效应的一种测试：纳米颗粒制备的起始材料、表面包覆剂、表面反应产生的物质、纳米颗粒在生物和环境介质中的转化副产物，以及纳米颗粒固有结构的变化。
