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营养与冠心病的最新科学与临床应用

Recent Science and Clinical Application of Nutrition to Coronary Heart Disease.

机构信息

a Associate Clinical Professor of Medicine, Vanderbilt University Medical School, Director, Hypertension Institute and Vascular Biology, Medical Director of Division of Human Nutrition, Saint Thomas Medical Group, Saint Thomas Hospital , Nashville , Tennessee , USA.

b University of Western States, Institute for Functional Medicine , Seattle , Washington , USA.

出版信息

J Am Coll Nutr. 2018 Mar-Apr;37(3):169-187. doi: 10.1080/07315724.2017.1381053. Epub 2018 Jan 9.

Abstract

One of the greatest threats to mortality in industrialized societies continues to be coronary heart disease (CHD). Moreover, the ability to decrease the incidence of CHD has reached a limit utilizing traditional diagnostic evaluations and prevention and treatment strategies for the top five cardiovascular risk factors (hypertension, diabetes mellitus, dyslipidemia, obesity, and smoking). It is well known that about 80% of CHD can be prevented with optimal nutrition, coupled with exercise, weight management, mild alcohol intake, and smoking cessation. Among all of these factors, optimal nutrition provides the basic foundation for prevention and treatment of CHD. Numerous prospective nutrition clinical trials have shown dramatic reductions in the incidence of CHD. As nutritional science and nutrigenomics research continues, our ability to adjust the best nutrition with an individualized approach is emerging. This article reviews the role of nutrition in the prevention and treatment of CHD and myocardial infarction (MI).

摘要

在工业化社会,导致死亡率的最大威胁之一仍然是冠心病(CHD)。此外,利用传统的诊断评估和针对五个主要心血管风险因素(高血压、糖尿病、血脂异常、肥胖和吸烟)的预防和治疗策略,降低 CHD 发病率的能力已达到极限。众所周知,通过优化营养,结合运动、体重管理、适度饮酒和戒烟,约 80%的 CHD 是可以预防的。在所有这些因素中,优化营养为 CHD 的预防和治疗提供了基本基础。大量前瞻性营养临床试验表明,CHD 的发病率显著降低。随着营养科学和营养基因组学研究的不断发展,我们以个体化方式调整最佳营养的能力正在显现。本文综述了营养在预防和治疗冠心病和心肌梗死(MI)中的作用。

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