Kellens A, De Buck E, Emonds M-P, Vandekerckhove P, Lagae L
Centre for Evidence-Based Practice, Belgian Red Cross, Mechelen, Belgium.
Department of Public Health and Primary Care, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Vox Sang. 2018 Feb;113(2):104-109. doi: 10.1111/vox.12618. Epub 2018 Jan 4.
Epilepsy is a common neurological disorder characterized by the appearance of seizures. Often, epilepsy patients are temporarily or permanently excluded from blood donation. To gain a better understanding of the policies that are currently applied, we performed a survey among blood services.
A cross-sectional, Web-based questionnaire using the online Questback tool was developed and distributed to 46 representatives of blood services worldwide. The questionnaire was composed of nine questions.
A total of 27 respondents, representing blood services in 26 countries on five continents, participated in the survey. Current policies range from permanent acceptance over temporary exclusion to permanent exclusion. Rationales for these different policies are diverse. The majority of blood services (59·3%) apply temporary exclusion as their policy, though no consensus exists on the length of time that epilepsy patients have to be medication-free or seizure-free. None of the respondents could provide data about adverse events in epilepsy patients during the blood donation process.
The results of this survey indicate a large discrepancy in policies applied worldwide. A lack of scientific evidence could be one of the underlying reasons. Therefore, it is of paramount importance to further research the potential risks for donors and recipients regarding blood donation by people with epilepsy. This can then serve as a base for evidence-based policymaking and lead to safer and more effective blood transfusion programmes.
癫痫是一种常见的神经系统疾病，其特征为发作。癫痫患者常常被暂时或永久禁止献血。为了更好地了解当前所应用的政策，我们对血液服务机构开展了一项调查。
使用在线Questback工具开发了一份基于网络的横断面调查问卷，并分发给全球46家血液服务机构的代表。该问卷由九个问题组成。
共有27名受访者参与了调查，他们代表五大洲26个国家的血液服务机构。当前政策从永久接纳到暂时排除再到永久排除不等。这些不同政策的依据各不相同。大多数血液服务机构（59.3%）将暂时排除作为其政策，不过对于癫痫患者必须无药物治疗或无发作的时长，并未达成共识。没有一位受访者能够提供癫痫患者在献血过程中不良事件的数据。
本次调查结果表明全球应用的政策存在很大差异。缺乏科学证据可能是根本原因之一。因此，进一步研究癫痫患者献血对献血者和受血者的潜在风险至关重要。这可为基于证据的政策制定提供依据，并带来更安全、更有效的输血计划。
