Quandt Jane E, Barletta Michele, Cornell Karen K, Giguère Steeve, Hofmeister Erik H
Department of Small Animal Medicine and Surgery (Quandt, Cornell, Hofmeister), and the Department of Large Animal Medicine (Barletta, Giguère), College of Veterinary Medicine, University of Georgia, Athens, GA 30602.
J Vet Emerg Crit Care (San Antonio). 2018 Jan;28(1):45-53. doi: 10.1111/vec.12686.
To assess agreement between a point-of-care glucometer (POCG) and a laboratory chemistry analyzer for blood glucose measurements in goats.
Prospective study.
University teaching hospital.
Eighteen healthy adult goats.
Whole blood samples were obtained via jugular venipuncture prior to premedication with xylazine and butorphanol (T0), following premedication (T20), and after 1 hour of inhalant anesthesia (T60). Each sample was tested with a POCG and a laboratory analyzer (HITA). Agreement was assessed using concordance correlation coefficients and calculation of bias and 95% limits of agreement.
Mean blood glucose concentration at T0 was 3.9 ± 0.6 mmol/L (70 ± 10 mg/dL; POCG) and 2.9 ± 0.4 mmol/dL (53 ± 8 mg/dL; HITA). Glucose concentrations at T20 were 6.7 ± 2.4 mmol/L (121 ± 43 mg/dL) and 5.4 ± 2.1 mmol/L (97 ± 37 mg/dL) and at T60 were 5.7 ± 1.7 mmol/L (102 ± 31 mg/dL) and 4.7 ± 1.3 mmol/L (85 ± 24 mg/dL) when measured with the POCG and HITA, respectively. The POCG overestimated blood glucose compared to the HITA. The bias ± SD was 1.08 ± 0.53 mmol/L (19.4 ± 9.5 mg/dL) (95% LOA 0.04 to 2.11 mmol/L [0.7 to 38.0 mg/dL]) and the concordance correlation coefficient was 0.82. After correcting the results of the POCG using a mixed-effects linear model, the bias was 0.0 ± 0.38 mmol/L (0.0 ± 6.8 mg/dL) (95% LOA ± 0.74 mmol/L [± 13.4 mg/dL]) and the concordance correlation coefficient was 0.98.
The POCG overestimated blood glucose concentrations in goats, compared to the HITA, but when the POCG concentrations were corrected, the agreement was excellent.
评估即时血糖仪（POCG）与实验室化学分析仪在山羊血糖测量中的一致性。
前瞻性研究。
大学教学医院。
18只健康成年山羊。
在使用赛拉嗪和美他多辛进行术前用药前（T0）、术前用药后（T20）以及吸入麻醉1小时后（T60），通过颈静脉穿刺采集全血样本。每个样本分别用POCG和实验室分析仪（HITA）进行检测。使用一致性相关系数以及偏差和95%一致性界限的计算来评估一致性。
T0时平均血糖浓度POCG为3.9±0.6 mmol/L（70±10 mg/dL），HITA为2.9±0.4 mmol/dL（53±8 mg/dL）。T20时POCG测得的血糖浓度为6.7±2.4 mmol/L（121±43 mg/dL），HITA为5.4±2.1 mmol/L（97±37 mg/dL）；T60时POCG测得的血糖浓度为5.7±1.7 mmol/L（102±31 mg/dL），HITA为4.7±1.3 mmol/L（85±24 mg/dL）。与HITA相比，POCG高估了血糖值。偏差±标准差为1.08±0.53 mmol/L（19.4±9.5 mg/dL）（95%一致性界限为0.04至2.11 mmol/L [0.7至38.0 mg/dL]），一致性相关系数为0.82。使用混合效应线性模型校正POCG的结果后，偏差为0.0±0.38 mmol/L（0.0±6.8 mg/dL）（95%一致性界限为±0.74 mmol/L [±13.4 mg/dL]），一致性相关系数为0.98。
与HITA相比，POCG高估了山羊的血糖浓度，但校正POCG浓度后，一致性极佳。
