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一种用于可视化检测光气的基于BODIPY的荧光探针:迈向手持式光气探测器的开发。

A BODIPY-Based Fluorescent Probe to Visually Detect Phosgene: Toward the Development of a Handheld Phosgene Detector.

作者信息

Sayar Melike, Karakuş Erman, Güner Tuğrul, Yildiz Busra, Yildiz Umit Hakan, Emrullahoğlu Mustafa

机构信息

Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Urla, 35430, Izmir, Turkey.

Chemistry Group Laboratories TUBITAK National Metrology Institute (UME), 41470, Gebze-Kocaeli, Turkey.

出版信息

Chemistry. 2018 Mar 2;24(13):3136-3140. doi: 10.1002/chem.201705613. Epub 2018 Feb 5.

DOI:10.1002/chem.201705613
PMID:29315879
Abstract

A boron-dipyrromethene (BODIPY)-based fluorescent probe with a phosgene-specific reactive motif shows remarkable selectivity toward phosgene, in the presence of which the nonfluorescent dye rapidly transforms into a new structure and induces a fluorescent response clearly observable to the naked eye under ultraviolet light. Given that dynamic, a prototypical handheld phosgene detector with a promising sensing capability that expedites the detection of gaseous phosgene without sophisticated instrumentation was developed. The proposed method using the handheld detector involves a rapid response period suitable for issuing early warnings during emergency situations.

摘要

一种具有光气特异性反应基序的基于硼二吡咯亚甲基(BODIPY)的荧光探针,对光气表现出显著的选择性。在光气存在的情况下,这种非荧光染料会迅速转变为新的结构,并在紫外光下引发肉眼清晰可见的荧光响应。鉴于其动态特性,开发了一种具有前景的传感能力的原型手持式光气探测器,该探测器无需复杂仪器即可快速检测气态光气。使用该手持式探测器的提议方法具有快速响应期,适合在紧急情况下发出早期预警。

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