Department of Rheumatology and Balneology, Jagiellonian University Medical College, 31-531, Krakow, Poland.
Department of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, 31-034, Krakow, Poland.
J Cancer Surviv. 2018 Jun;12(3):326-333. doi: 10.1007/s11764-017-0672-6. Epub 2018 Jan 9.
The purpose of this study is to characterize health status of older cancer survivors using data from the population-based PolSenior study.
We compared cancer survivors and non-cancer subjects according to comorbidities, functional status, mental health, and sociodemographic factors.
There were 286 (5.8%) cancer survivors in a population of 4943 adults aged 65 years and older. The mean age of cancer survivors was 79.4 ± 8.2 years and the median time since cancer diagnosis was 8.5 years (Q1-Q3: 4-16 years). After adjustment for age, sex, education, marital status, and number of comorbidities, compared with a non-cancer population, cancer survivors were more likely to experience falls (OR = 1.38; 95% CI: 1.04-1.83), and to report poor health (OR = 1.49; 95%CI: 1.83-2.06), but cancer survivorship was not associated with impairments in instrumental activities of daily living (IADLs). Age and university education, but neither the time from cancer diagnosis nor the number of comorbidities, were associated with impairments in cancer survivors. Three or more chronic diseases were found in over 50% of cancer survivors and in 38% of the non-cancer population (p < 0.001).
Cancer survivors over the age of 65 years have a higher prevalence of falls, are more likely to report poor health status, and have a higher number of chronic conditions than the non-cancer population, but they maintain independence in IADLs. Advanced age and elementary education are associated with increased occurrence of functional impairments in older cancer survivors IMPLICATIONS FOR CANCER SURVIVORS: Older cancer survivors may require preventive services to reduce the risk of functional decline.
本研究旨在利用基于人群的 PolSenior 研究的数据来描述老年癌症幸存者的健康状况。
我们根据合并症、功能状态、心理健康和社会人口因素比较了癌症幸存者和非癌症患者。
在 4943 名 65 岁及以上成年人中，有 286 名（5.8%）癌症幸存者。癌症幸存者的平均年龄为 79.4±8.2 岁，癌症诊断后中位时间为 8.5 年（四分位距 1-16 年）。在校正年龄、性别、教育程度、婚姻状况和合并症数量后，与非癌症人群相比，癌症幸存者更有可能经历跌倒（OR=1.38；95%CI：1.04-1.83），并报告健康状况较差（OR=1.49；95%CI：1.83-2.06），但癌症存活与工具性日常生活活动（IADLs）受损无关。年龄和大学教育，但癌症诊断后时间和合并症数量均与癌症幸存者的受损无关。超过 50%的癌症幸存者和 38%的非癌症人群患有三种或更多种慢性病（p<0.001）。
65 岁以上的癌症幸存者跌倒的发生率更高，更有可能报告健康状况较差，并且患有慢性病的人数多于非癌症人群，但他们在 IADLs 方面保持独立。年龄较大和小学教育与老年癌症幸存者功能障碍的发生率增加有关。
老年癌症幸存者可能需要预防服务来降低功能下降的风险。
