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国际抗癫痫联盟发作和癫痫分类:对临床的影响。

The ILAE classification of seizures and epilepsies: implications for the clinic.

机构信息

a Laboratory of Neurological Disorders, Department of Neuroscience , IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri" , Milan , Italy.

b NIHR University College London Hospitals Biomedical Research Centre , UCL Institute of Neurology , London WC1N 3BG, Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ , United Kingdom.

出版信息

Expert Rev Neurother. 2018 Mar;18(3):179-183. doi: 10.1080/14737175.2018.1427066. Epub 2018 Jan 17.

Abstract

The classification of epileptic seizures and the epilepsies has recently been revised by the International League Against Epilepsy (ILAE) and a new classification scheme issued. Areas covered: The new classification scheme has been critically appraised in the light of the previous classifications and subsequent revisions. The purposes of the classification and its potential use have been extensively discussed. Expert commentary: This ILAE classification scheme, the latest of a series of proposals published in the last 30 years, has made progress as it has a multi-level structure (seizure types, epilepsy types, epilepsy syndromes) allowing for differing uses and combines the previously separate seizure types and epilepsies schemes into a single instrument. Seizures and epilepsies can also be classified based on the available diagnostic aids, which may differ substantially between counties with mature economies and resource-poor countries. An intrinsic limitation of the classification, however, is the attempt to box cases as seen in clinical practice into schematic categories, leaving no room for variants and atypical clinical presentations. Another limitation is the lack of flexibility which hampers the ability to link the instrument to the preceding classifications in order to preserve continuity and monitor disease trends in time and space.

摘要

癫痫发作和癫痫的分类最近已被国际抗癫痫联盟 (ILAE) 修订,并发布了新的分类方案。

涵盖领域

根据之前的分类和随后的修订,对新的分类方案进行了批判性评估。对分类的目的及其潜在用途进行了广泛的讨论。

专家评论

作为过去 30 年来发布的一系列提案中的最新提案,该 ILAE 分类方案在以下方面取得了进展:它具有多层次结构(发作类型、癫痫类型、癫痫综合征),允许不同的用途,并将之前分开的发作类型和癫痫方案合并为一个单一的工具。根据现有的诊断辅助工具,发作和癫痫也可以进行分类,而在成熟经济体和资源匮乏国家之间,这些辅助工具可能有很大差异。然而,分类的一个内在局限性是试图将临床上所见的病例归入示意性类别,没有为变体和非典型临床表现留出空间。另一个限制是缺乏灵活性,这阻碍了将该工具与之前的分类联系起来的能力,以便保持连续性并及时监测疾病在时间和空间上的趋势。

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