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小儿膝关节手术周围神经阻滞后的残留神经症状

Residual Neurological Symptoms After Peripheral Nerve Blocks for Pediatric Knee Surgery.

作者信息

Tamai Robert J, Sullivan Brian T, Lee Rushyuan J

机构信息

Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD.

出版信息

J Pediatr Orthop. 2018 Mar;38(3):e157-e161. doi: 10.1097/BPO.0000000000001125.

Abstract

BACKGROUND

Peripheral nerve blocks (PNBs) provide excellent pain control and reduce the need for systemic analgesics in orthopaedic surgery. PNBs rarely cause complications; however, a few studies of adults have reported neurological complications during the early postoperative period. We investigated complications associated with the use of PNBs during pediatric knee surgery.

METHODS

We reviewed the medical records of all 121 children (aged ≤18 y) who underwent knee surgery by 1 orthopaedic surgeon between October 2014 and September 2016. One hundred of these patients had PNBs. The primary outcome of interest was postoperative neurological symptoms. Other study parameters were patient characteristics, surgical details, tourniquet use/duration of use, PNB guidance method and anatomic location, and PNB-associated procedural complications (eg, blood loss, anesthetic neurotoxicity). Data were analyzed using Student t tests and Fisher exact tests, with significance at P<0.05.

RESULTS

Of the 100 patients with PNBs, 23 had persistent lower-extremity paresthesias postoperatively. Most paresthesias were attributed to the surgical procedure; however, at first follow-up (mean, 1.6±0.4 wk) 6 patients had paresthesias and other neurological symptoms proximal to the knee in a distribution pattern consistent with the PNB. Three of these were unresolved at last follow-up (mean, 56±37 wk). All neurological symptoms were associated with femoral nerve blocks. The 6 patients with suspected PNB-associated neurological symptoms had a significantly higher mean BMI (31±5.5) than the 94 patients without symptoms (23±6.1; P=0.002). Obesity was associated with PNB-associated neurological symptoms (P=0.002), as was female sex (P<0.001). No significant differences were found in terms of age, surgery duration, or tourniquet use/duration of use. Most PNB procedures used ultrasound guidance, and no procedural complications were reported.

CONCLUSIONS

Compared with previous studies, we report a higher rate (6%) of PNB-associated neurological symptoms in children after knee surgery with PNBs. Obesity and female sex were associated with persistent neurological symptoms in the distribution pattern of the PNB.

LEVEL OF EVIDENCE

Level III (retrospective comparative study).

摘要

背景

周围神经阻滞(PNB)在骨科手术中能提供出色的疼痛控制,并减少全身镇痛药的使用需求。PNB很少引起并发症;然而,一些针对成人的研究报告了术后早期的神经并发症。我们调查了小儿膝关节手术中使用PNB相关的并发症。

方法

我们回顾了2014年10月至2016年9月间由1名骨科医生为121名儿童(年龄≤18岁)实施膝关节手术的病历。其中100例患者接受了PNB。主要关注的结局是术后神经症状。其他研究参数包括患者特征、手术细节、止血带使用情况/使用时长、PNB引导方法和解剖位置,以及与PNB相关的操作并发症(如失血、麻醉剂神经毒性)。数据采用Student t检验和Fisher精确检验进行分析,P<0.05具有统计学意义。

结果

在100例接受PNB的患者中,23例术后出现持续性下肢感觉异常。大多数感觉异常归因于手术操作;然而,在首次随访时(平均1.6±0.4周),6例患者在膝关节近端出现感觉异常及其他神经症状,其分布模式与PNB一致。其中3例在末次随访时(平均56±37周)仍未缓解。所有神经症状均与股神经阻滞有关。6例疑似与PNB相关神经症状的患者平均BMI(31±5.5)显著高于94例无症状患者(23±6.1;P=0.002)。肥胖与PNB相关神经症状有关(P=0.002),女性也是如此(P<0.001)。在年龄、手术时长或止血带使用情况/使用时长方面未发现显著差异。大多数PNB操作采用超声引导,未报告操作并发症。

结论

与以往研究相比,我们报告了小儿膝关节手术中使用PNB后PNB相关神经症状的发生率较高(6%)。肥胖和女性与PNB分布模式下的持续性神经症状有关。

证据级别

III级(回顾性比较研究)。

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